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CAS 10162-58-0

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7-methylguanosine-5'-monophosphate

Description:
7-Methylguanosine-5'-monophosphate (7-mGMP) is a nucleotide derivative of guanosine, characterized by the presence of a methyl group at the nitrogen-7 position of the guanine base. This modification is significant in biological systems, particularly in RNA metabolism, where it plays a crucial role in the stability and function of RNA molecules. 7-mGMP is involved in the capping of mRNA, which protects the RNA from degradation and assists in the initiation of translation. The compound features a ribose sugar linked to a phosphate group at the 5' position, contributing to its role in cellular signaling and as a building block for RNA synthesis. In terms of solubility, 7-mGMP is typically soluble in water, which facilitates its biological functions. Its CAS number, 10162-58-0, is used for identification in chemical databases. Overall, 7-methylguanosine-5'-monophosphate is an essential molecule in molecular biology, influencing gene expression and cellular processes.
Formula:C11H16N5O8P
InChI:InChI=1S/C11H16N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,22)/p+1/t4-,6-,7-,10-/m1/s1
InChI key:AOKQNZVJJXPUQA-KQYNXXCUSA-O
SMILES:CN1C=[N+](C2=C1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O
Synonyms:
  • 7-methylguanosine-5'-monophosphate
  • 1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-9-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt
  • 7-Methylguanosine 5'-phosphate
  • 7-Methyl GMP
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