CAS 101622-53-1

2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine

Description:

2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine, with the CAS number 101622-53-1, is a purine derivative characterized by its complex structure, which includes a purine ring system substituted with a chlorine atom and a methyl group at specific positions. This compound features an amine functional group, contributing to its potential reactivity and biological activity. The presence of the phenylmethyl group enhances its lipophilicity, which may influence its interaction with biological targets. Typically, such compounds are of interest in medicinal chemistry due to their potential pharmacological properties, including antiviral or anticancer activities. The chlorine substitution can also affect the compound's electronic properties and stability. In terms of solubility, purine derivatives often exhibit variable solubility in polar and non-polar solvents, which can impact their formulation and application in drug development. Overall, 2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine represents a class of compounds that may have significant implications in pharmaceutical research and development.

Formula: C₁₃H₁₂ClN₅

InChI: InChI=1S/C13H12ClN5/c1-19-8-16-10-11(17-13(14)18-12(10)19)15-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,15,17,18)

InChI key: InChIKey=QNKNBVBQFILDGJ-UHFFFAOYSA-N

SMILES: N(CC1=CC=CC=C1)C2=C3C(=NC(Cl)=N2)N(C)C=N3

Synonyms:

• 2-Chloro-6-benzylamino-9-methylpurine
• 2-Chloro-9-methyl-6-(benzylamino)purine
• 2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine
• 6-(Benzylamino)-2-chloro-9-methylpurine
• 9H-purin-6-amine, 2-chloro-9-methyl-N-(phenylmethyl)-
• N-benzyl-2-chloro-9-methyl-9H-purin-6-amine

9H-Purin-6-amine, 2-chloro-9-methyl-N-(phenylmethyl)-

CAS: 101622-53-1

Formula: C₁₃H₁₂ClN₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 273.7209

Ref: IN-DA0004Z6

CDK2-IN-13

CAS: 101622-53-1

CDK2-IN-13

Formula: C₁₃H₁₂ClN₅

Purity: 98%

Molecular weight: 273.73

Ref: 54-OR1036113

2-Chloro-9-methyl-6-(benzylamino)purine (>90%)

Controlled Product

CAS: 101622-53-1

Applications 2-Chloro-9-methyl-6-(benzylamino)purine is an intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest.
References Liang, M., et al.: Med. Chem. Lett., 3, 985 (2012); Havlicek, L., et al.: J. Med. Chem., 40, 408 (1997); Gonazalez, M.P., et al.: Bull. Math. Biol., 68, 735 (2006); Parker, C. W., et al.: Phytochem., 25, 303 (1986);

Formula: C₁₃H₁₂ClN₅

Purity: >90%

Color and Shape: Neat

Molecular weight: 273.72

Ref: TR-C368860

N-Benzyl-2-chloro-9-methyl-9H-purin-6-amine

CAS: 101622-53-1

N-Benzyl-2-chloro-9-methyl-9H-purin-6-amine

Formula: C₁₃H₁₂ClN₅

Purity: 99%

Molecular weight: 273.72

Ref: IN-DG162233

N-Benzyl-2-chloro-9-methyl-9H-purin-6-amine

CAS: 101622-53-1

Purity: 98%

Molecular weight: 273.7200012

Ref: 10-F907373

2-Chloro-9-methyl-6-(benzylamino)purine-d3

Controlled Product

CAS: 101622-53-1

Applications 2-Chloro-9-methyl-6-(benzylamino)purine-d3 is an isotope labelled intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest.
References Liang, M., et al.: Med. Chem. Lett., 3, 985 (2012); Havlicek, L., et al.: J. Med. Chem., 40, 408 (1997); Gonazalez, M.P., et al.: Bull. Math. Biol., 68, 735 (2006); Parker, C. W., et al.: Phytochem., 25, 303 (1986);

Formula: C₁₃H₉D₃ClN₅

Color and Shape: Neat

Molecular weight: 276.74

Ref: TR-C368862

CDK2-IN-13

CAS: 101622-53-1

CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.

Formula: C₁₃H₁₂ClN₅

Color and Shape: Solid

Molecular weight: 273.721

Ref: TM-T60154