CAS 1018069-81-2

Formula: C33H31Cl2N5O3

InChI: InChI=1S/C33H30ClN5O3.ClH/c1-22-19-24(28-21-27(13-14-29(28)34)42-32(40)23-7-3-2-4-8-23)20-30-31(22)36-33(38-37-30)35-25-9-11-26(12-10-25)41-18-17-39-15-5-6-16-39;/h2-4,7-14,19-21H,5-6,15-18H2,1H3,(H,35,36,38);1H

InChI key: VLWKPMDUDFMWBO-UHFFFAOYSA-N

SMILES: CC1=CC(=CC2=C1N=C(N=N2)NC3=CC=C(C=C3)OCCN4CCCC4)C5=C(C=CC(=C5)OC(=O)C6=CC=CC=C6)Cl.Cl

4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)benzo[E][1,2,4]triazin-7-yl)phenyl benzoate hydrochloride

CAS: 1018069-81-2

4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)benzo[E][1,2,4]triazin-7-yl)phenyl benzoate hydrochloride is a potent inhibitor of the fibroblast growth factor receptor 1 (FGFR1). FGFR1 signaling promotes the growth of blood vessels and tissues, including pancreatic β cells. The inhibition of this receptor blocks the proliferation of both endothelial cells and pluripotent stem cells. This drug is biocompatible and can be used for implanting tissues in vivo. 4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)benzo[E][1,2,4]triazin-7-yl)phenyl ben

Formula: C₃₃H₃₁Cl₂N₅O₃

Purity: Min. 95%

Molecular weight: 616.5 g/mol

Ref: 3D-TQB06981

TG 100801 Hydrochloride

CAS: 1018069-81-2

TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.

Formula: C₃₃H₃₁Cl₂N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 616.54

Ref: TM-T13157L