CAS 101827-46-7: Butenafine hydrochloride

Description:Butenafine hydrochloride is an antifungal agent primarily used in the treatment of dermatophyte infections, such as athlete's foot and ringworm. It belongs to the class of compounds known as benzylamines and functions by inhibiting the enzyme squalene epoxidase, which is crucial in the biosynthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to the accumulation of toxic sterols and ultimately results in fungal cell death. Butenafine hydrochloride is typically administered topically, and its formulation may include various excipients to enhance skin penetration and stability. The compound is characterized by its white to off-white crystalline appearance and is soluble in organic solvents. Its safety profile indicates that it is generally well-tolerated, with minimal systemic absorption when used as directed. However, like all medications, it may cause localized skin reactions in some individuals. Overall, butenafine hydrochloride is an effective option for managing superficial fungal infections.

Formula:C₂₃H₂₇N·ClH

InChI:InChI=1S/C23H27N.ClH/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20;/h5-15H,16-17H2,1-4H3;1H

InChI key:InChIKey=LJBSAUIFGPSHCN-UHFFFAOYSA-N

SMILES:Cl.C=1C=CC2=C(C1)C=CC=C2CN(C)CC3=CC=C(C=C3)C(C)(C)C

Synonyms:
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine hydrochloride (1:1)
1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride
1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1)
Butenafine Hydrochloride
Butenafine hydrochloide
ButenafineHCL
Kp-363
Mentax
N-((4-(1,1-Dimethylethyl)Phenyl)Methyl)-N-Methyl-1-Naphthalenemethanaminehyd
See more synonyms
N-((4-(1,1-Dimethylethyl)Phenyl)Methyl)-N-Methyl-1-Naphthalenemethanaminhy
N-(4-Tert-Butylbenzyl)-N-Methyl-1-Naphthalenemethylamine Hydrochloride
N-(4-t-Butylbenzyl)-N-Methyl-1-naphthalenemethylamine hydrochloride
Scorba

Found 12 products.

Product data	Purity	Price range	Estimated delivery
Butenafine Hydrochloride (1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride) REF: 45-1081952CAS: 101827-46-7	- - -	409.00 €	Mon 14 Apr 25
Butenafine hydrochloride REF: TM-T1217CAS: 101827-46-7	100% - 99.66%	37.00 €~88.00 €	Tue 15 Apr 25
1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1) REF: IN-DA0005NOCAS: 101827-46-7	98%	To inquire	Tue 15 Apr 25
Butenafine HCl REF: 4Z-B-661CAS: 101827-46-7	- - -	To inquire	Wed 16 Apr 25
Butenafine hydrochloride REF: 54-OR1029299CAS: 101827-46-7	- - -	32.00 €~1,391.00 €	Wed 16 Apr 25
Butenafine hydrochloride REF: 54-BUP17756CAS: 101827-46-7	99.9%	54.00 €~132.00 €	Wed 16 Apr 25
Butenafine hydrochloride REF: 7W-GP2594CAS: 101827-46-7	≥ 99.0%	To inquire	Wed 16 Apr 25
Butenafine-13C-d3 HCl REF: 4Z-B-6610CAS: 101827-46-7	- - -	To inquire	Wed 16 Apr 25
Butenafine Hydrochloride REF: 3B-B3293CAS: 101827-46-7	>98.0%(T)(HPLC)	42.00 €~126.00 €	Mon 21 Apr 25
Butenafine Hydrochloride REF: TR-B690195CAS: 101827-46-7	- - -	140.00 €~270.00 €	Fri 25 Apr 25
Butenafine hydrochloride REF: 3D-FB19376CAS: 101827-46-7	Min. 95%	80.00 €~1,005.00 €	Mon 28 Apr 25
Butenafine hydrochloride REF: 10-F517737CAS: 101827-46-7	0.97	- - -	Discontinued product