CAS 1018679-79-2

Formula: C26H25F4N3O3S

InChI: InChI=1S/C26H25F4N3O3S/c1-2-36-17-25-14-18-15-31-33(22-7-5-21(27)6-8-22)24(18)13-20(25)11-12-32(16-25)37(34,35)23-9-3-19(4-10-23)26(28,29)30/h3-10,13,15H,2,11-12,14,16-17H2,1H3/t25-/m1/s1

InChI key: SLKURXRZHJOZOD-RUZDIDTESA-N

SMILES: CCOC[C@]12CC3=C(C=C1CCN(C2)S(=O)(=O)C4=CC=C(C=C4)C(F)(F)F)N(N=C3)C5=CC=C(C=C5)F

1H-Pyrazolo[3,4-g]isoquinoline, 4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-6-[[4-(trifluoromethyl)phenyl]sulfonyl]-, (4aR)-

CAS: 1018679-79-2

Formula: C₂₆H₂₅F₄N₃O₃S

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 535.5536

Ref: IN-DA0005SV

Cort108297

CAS: 1018679-79-2

Cort108297

Formula: C₂₆H₂₅F₄N₃O₃S

Purity: 99.5%

Molecular weight: 535.55

Ref: 54-BUP08462

cort-108297

CAS: 1018679-79-2

Cort-108297 is a glucocorticoid receptor agonist that can regulate the body's response to stress. It is a synthetic compound that binds to the glucocorticoid receptor and activates it, leading to a number of physiological effects. Cort-108297 has been shown to have locomotor activity in mice infected with herpes simplex virus. This drug also interacts with the glucocorticoid receptor to increase transcription of tumor necrosis factor-α (TNF-α) and cyclooxygenase 2 (COX-2) genes in cervical cancer cells. Cort-108297 has also been shown to inhibit prostate cancer cell growth and primary breast cancer development in animal models. In addition, cort-108297 has been shown to activate toll-like receptors on macrophages, which may be involved in its anti-inflammatory properties.

Formula: C₂₆H₂₅F₄N₃O₃S

Purity: Min. 95%

Molecular weight: 535.56 g/mol

Ref: 3D-TQB67979

Cort108297

CAS: 1018679-79-2

Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.

Formula: C₂₆H₂₅F₄N₃O₃S

Purity: 98.36% - 99.94%

Color and Shape: Purple Solid

Molecular weight: 535.554

Ref: TM-T15000