CAS 10212-31-4

2-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone

Description:

2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone, with CAS number 10212-31-4, is a nucleoside analog that exhibits structural similarities to naturally occurring nucleosides. This compound features a β-D-arabinofuranosyl sugar moiety, which contributes to its biological activity. The presence of the amino group at the 2-position and the methyl group at the 5-position of the pyrimidine ring are significant for its interaction with biological targets, particularly in nucleic acid synthesis and metabolism. This compound has garnered interest in medicinal chemistry due to its potential antiviral and anticancer properties, as it may interfere with nucleic acid synthesis in pathogens or cancer cells. Its solubility and stability in biological systems are important characteristics that influence its pharmacokinetics and therapeutic efficacy. Additionally, the compound's ability to mimic natural nucleosides allows it to be incorporated into RNA or DNA, potentially disrupting normal cellular functions. Overall, 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone represents a valuable compound in the exploration of new therapeutic agents.

Formula: C₁₀H₁₅N₃O₅

InChI: InChI=1S/C10H15N3O5/c1-4-2-13(10(11)12-8(4)17)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7+,9-/m1/s1

InChI key: InChIKey=JUFWRFOUTDSMSO-JAGXHNFQSA-N

SMILES: O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=NC(=O)C(C)=C2

Synonyms:

• 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone
• 4(1H)-Pyrimidinone, 2-amino-1-β-D-arabinofuranosyl-5-methyl-

2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone

CAS: 10212-31-4

Nucleoside Derivatives - Arabino-nucleosides, Iso-cytidine derivatives

Formula: C₁₀H₁₅N₃O₅

Color and Shape: Solid

Molecular weight: 257.24

Ref: TM-TNU0353

2-Amino-1-(b-D-arabinofuranosyl)-5-methyl-4(1H)-pyrimidinone

CAS: 10212-31-4

2-Amino-1-(b-D-arabinofuranosyl)-5-methyl-4(1H)-pyrimidinone (araA) is an activator of nucleoside synthesis. It is a novel and versatile chemical that can be used to produce both ribonucleosides and deoxyribonucleosides. AraA is a potent antiviral and anticancer agent that has been shown to inhibit the growth of cancer cells in vitro. AraA is a modified form of 2′,3′-dideoxyadenosine, which is synthesized by enzymatic modification of natural 2′,3′ dideoxythymidine.

Purity: Min. 95%

Ref: 3D-NA163027