CAS 102146-07-6

DPCPX

Description:

DPCPX, or 1,3-Dipropyl-8-cyclopentylxanthine, is a selective antagonist of the adenosine A1 receptor, which plays a crucial role in various physiological processes, including neurotransmission and cardiovascular function. This compound is characterized by its xanthine structure, which is modified with propyl and cyclopentyl groups, enhancing its selectivity and potency for the A1 receptor. DPCPX is typically used in pharmacological research to study the effects of adenosine receptor modulation on various biological systems. It is known for its ability to inhibit the actions of adenosine, thereby influencing processes such as heart rate and neurotransmitter release. The compound is often utilized in experimental settings to explore potential therapeutic applications, particularly in conditions where adenosine signaling is implicated, such as ischemia or neurodegenerative diseases. DPCPX is usually handled with care in laboratory environments, adhering to safety protocols due to its biological activity.

Formula: C₁₆H₂₄N₄O₂

InChI: InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)

InChI key: InChIKey=FFBDFADSZUINTG-UHFFFAOYSA-N

SMILES: C(CC)N1C2=C(NC(=N2)C3CCCC3)C(=O)N(CCC)C1=O

Synonyms:

• 1,3-Dipropyl-8-cyclopentylxanthine
• 1,3-Dpcpx
• 1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-
• 1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-
• 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione
• 8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione
• 8-cyclopentyl-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione
• Dpcpx
• Pd 116948
• 8-Cyclopentyl-1,3-dipropylxanthine
• 8-Cyclopentyl-1,3-dipropylxanthine

1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-

CAS: 102146-07-6

Formula: C₁₆H₂₄N₄O₂

Purity: %

Color and Shape: Solid

Molecular weight: 304.3874

Ref: IN-DA0006QF

DPCPX

CAS: 102146-07-6

DPCPX

Purity: ≥98%

Molecular weight: 304.39g/mol

Ref: 54-BUP11535

DPCPX

CAS: 102146-07-6

DPCPX (PD 116948) is an A1 adenosine receptor antagonist

Formula: C₁₆H₂₄N₄O₂

Purity: 99.23% - 99.93%

Color and Shape: White Solid

Molecular weight: 304.39

Ref: TM-T22744

8-CYCLOPENTYL-1,3-DIPROPYL-1H-PURINE-2,6(3H,7H)-DIONE

CAS: 102146-07-6

Purity: 95%

Molecular weight: 304.3940124511719

Ref: 10-F799880

8-Cyclopentyl-1,3-dipropylxanthine

Controlled Product

CAS: 102146-07-6

Applications DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.
References Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),

Formula: C₁₆H₂₄N₄O₂

Color and Shape: Neat

Molecular weight: 304.39

Ref: TR-C988500

8-Cyclopentyl-1,3-dipropylxanthine

Controlled Product

CAS: 102146-07-6

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is an adenosine receptor antagonist that blocks the binding of adenosine to its receptor. DPCPX has been shown to be effective in preventing neuronal death in experimental models and has been shown to have a protective effect against myocardial infarct. This drug also inhibits glutamate release from nerve endings and prevents the activation of P2Y receptors. DPCPX can also inhibit the activity of cyclase enzymes, which are responsible for producing cyclic AMP and cAMP from ATP. DPCPX is a water-soluble ester hydrochloride that can be used as an anti-inflammatory agent.

Formula: C₁₆H₂₄N₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 304.39 g/mol

Ref: 3D-FC10753

8-Cyclopentyl-1,3-dipropylxanthine

CAS: 102146-07-6

Formula: C₁₆H₂₄N₄O₂

Molecular weight: 304.39

Ref: ST-EA-CP-A88099