CAS 1022-79-3: 5-Bromo-2′-deoxycytidine

Description: 5-Bromo-2′-deoxycytidine (5-BdC) is a synthetic nucleoside analog of deoxycytidine, characterized by the presence of a bromine atom at the 5-position of the pyrimidine ring. Its molecular formula is C₁₃H₁₄BrN₃O₅, and it has a molecular weight of approximately 327.17 g/mol. This compound is primarily used in molecular biology and biochemistry as a tool for studying DNA methylation and epigenetic modifications, as it can be incorporated into DNA during replication. 5-BdC can inhibit DNA synthesis and is often employed in research related to cancer and cellular differentiation. It exhibits properties such as solubility in water and organic solvents, making it versatile for laboratory applications. Additionally, 5-Bromo-2′-deoxycytidine can induce cytotoxic effects in rapidly dividing cells, which is a characteristic that has been explored in therapeutic contexts. However, its use requires careful handling due to potential mutagenic effects and the need for appropriate safety measures in laboratory settings.

Formula: C₉H₁₂BrN₃O₄

InChI: InChI=1S/C9H12BrN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1

InChI key: InChIKey=KISUPFXQEHWGAR-RRKCRQDMSA-N

SMILES: O=C1N=C(N)C(Br)=CN1C2OC(CO)C(O)C2

Synonyms:

• 4-amino-5-bromo-1-(2-deoxypentofuranosyl)pyrimidin-2(1H)-one
• 4-amino-5-bromo-1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidin-2(1H)-one
• 5-Bromodeoxycytidine
• Bcdr
• Brcdr
• Brn 0027385
• Bromodeoxycytidine
• C.A.S. 1,022,793
• Cytidine, 5-bromo-2'-deoxy-
• Nsc 61765
• 5-Bromo-2'-deoxycytidine
• 5-Bromo-2′-deoxycytidine
• 4-25-00-03689 (Beilstein Handbook Reference)

5-Bromo-2'-deoxycytidine, 99%

CAS: 1022-79-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₉H₁₁BrN₂O₅
• Purity: 99%
• Molecular weight: 307.1

Cytidine, 5-bromo-2'-deoxy-

CAS: 1022-79-3

• Formula: C₉H₁₂BrN₃O₄
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 306.1133

5-Bromo-2''-deoxycytidine

CAS: 1022-79-3

• Formula: C₉H₁₁BrN₂O₅
• Molecular weight: 307.10

4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

CAS: 1022-79-3

• Purity: 95.0%
• Color and Shape: Liquid, No data available.
• Molecular weight: 306.1159973144531

5-Bromo-2'-deoxycytidine

CAS: 1022-79-3

5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is …

• Formula: C₉H₁₂BrN₃O₄
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 306.11 g/mol