CymitQuimica logo

CAS 1022-79-3

:

5-Bromo-2′-deoxycytidine

Description:
5-Bromo-2′-deoxycytidine (5-BdC) is a synthetic nucleoside analog of deoxycytidine, characterized by the presence of a bromine atom at the 5-position of the pyrimidine ring. Its molecular formula is C₁₃H₁₄BrN₃O₅, and it has a molecular weight of approximately 327.17 g/mol. This compound is primarily used in molecular biology and biochemistry as a tool for studying DNA methylation and epigenetic modifications, as it can be incorporated into DNA during replication. 5-BdC can inhibit DNA synthesis and is often employed in research related to cancer and cellular differentiation. It exhibits properties such as solubility in water and organic solvents, making it versatile for laboratory applications. Additionally, 5-Bromo-2′-deoxycytidine can induce cytotoxic effects in rapidly dividing cells, which is a characteristic that has been explored in therapeutic contexts. However, its use requires careful handling due to potential mutagenic effects and the need for appropriate safety measures in laboratory settings.
Formula:C9H12BrN3O4
InChI:InChI=1S/C9H12BrN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
InChI key:InChIKey=KISUPFXQEHWGAR-RRKCRQDMSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(Br)C(N)=N1
Synonyms:
  • 4-amino-5-bromo-1-(2-deoxypentofuranosyl)pyrimidin-2(1H)-one
  • 4-amino-5-bromo-1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidin-2(1H)-one
  • 5-Bromodeoxycytidine
  • Bcdr
  • Brcdr
  • Brn 0027385
  • Bromodeoxycytidine
  • C.A.S. 1,022,793
  • Cytidine, 5-bromo-2'-deoxy-
  • Nsc 61765
  • See more synonyms
Found 6 products.