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CAS 102209-75-6

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C6-(N1-methyl-1,2,3-trazolylmethylene)penem

Description:
C6-(N1-methyl-1,2,3-trazolylmethylene)penem, with the CAS number 102209-75-6, is a synthetic compound belonging to the penem class of antibiotics, which are characterized by their beta-lactam structure. This compound features a unique substitution at the C6 position, where a 1,2,3-triazole moiety is incorporated, enhancing its antibacterial properties. The presence of the methyl group on the triazole ring contributes to its lipophilicity, potentially improving membrane permeability and bioavailability. Penems are known for their broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making them valuable in treating infections. The specific structural modifications in C6-(N1-methyl-1,2,3-trazolylmethylene)penem may also influence its resistance to beta-lactamases, enzymes produced by some bacteria that confer resistance to beta-lactam antibiotics. Overall, this compound represents a significant area of research in antibiotic development, aiming to combat antibiotic resistance and improve therapeutic efficacy.
Formula:C10H9N4NaO3S
InChI:InChI=1/C10H10N4O3S.Na/c1-13-3-5(11-12-13)2-6-8(15)14-7(10(16)17)4-18-9(6)14;/h2-3,7,9H,4H2,1H3,(H,16,17);/q;+1/p-1/b6-2-;
InChI key:OMJBLZMKGVWHQP-MPXWGJQKSA-M
SMILES:Cn1cc(C=C2C(=O)N3C(CSC23)C(=O)O)nn1.[Na]
Synonyms:
  • Brl 42715
  • 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1-methyl-1H-1,2,3-triazol-4-yl)methylene)-7-oxo-, sodium salt, (R-(Z))-
  • sodium (5R,6E)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methylidene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
  • sodium (6Z)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methylidene]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • C6-(N1-Methyl-1,2,3-trazolylmethylene)penem
Found 2 products.