CAS 102212-98-6: Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Description: Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a complex nucleoside derivative used primarily in the field of molecular biology and biochemistry, particularly in the synthesis of oligonucleotides. This compound features a cytidine base, which is a nucleoside composed of a pyrimidine base (cytosine) and a sugar (deoxyribose), modified with a benzoyl group and a phosphoramidite moiety. The presence of the phosphoramidite group allows for efficient coupling during oligonucleotide synthesis, making it a valuable reagent in the production of DNA and RNA sequences. The additional aromatic groups, such as bis(4-methoxyphenyl) and phenylmethyl, contribute to the compound's stability and solubility characteristics. This substance is typically handled under controlled conditions due to its reactivity and potential hazards associated with its chemical structure. Overall, it plays a significant role in advancing genetic research and therapeutic applications.

Formula: C₄₆H₅₂N₅O₈P

InChI: InChI=1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1

InChI key: InChIKey=PGTNFMKLGRFZDX-SALLYJDFSA-N

SMILES: N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=CC(=NC5=O)NC(=O)C=6C=CC=CC6)N(C(C)C)C(C)C

Synonyms:

• 5'-O-(4,4'-Dimethoxytrityl)-N4-Benzoyl-2'-Deoxycytidine-3'-(2-Cyanoethyl-N,N-Diisopropyl)Phosphoramidite
• Bz-dC Phosphoramidite
• Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
• DNA C Phosphoramidite
• N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
• N⁴-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
• N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

DMT-dC(bz) Phosphoramidite

CAS: 102212-98-6

• Formula: C₄₆H₅₂N₅O₈P
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 833.92

Bz dC β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)

CAS: 102212-98-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₄₆H₅₂N₅O₈P
• Color and Shape: White Powder
• Molecular weight: 833.35535

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS: 102212-98-6

• Formula: C₄₆H₅₂N₅O₈P
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 833.9075

DMT-dC(bz) Phosphoramidite

CAS: 102212-98-6

• Purity: 98%
• Molecular weight: 833.91g/mol

N4-Benzoyl-2''-deoxy-5''-O-DMT-cytidine 3''-CE phosphoramidite

CAS: 102212-98-6

DMT-dC(bz) Phosphoramidite

CAS: 102212-98-6

• Molecular weight: 833.923

DMT-dC(bz) Phosphoramidite

CAS: 102212-98-6

DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA[1].

• Formula: C₄₆H₅₂N₅O₈P
• Color and Shape: Liquid
• Molecular weight: 833.91

N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite

CAS: 102212-98-6

Please enquire for more information about N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite including the price, delivery time and …

• Formula: C₄₆H₅₂N₅O₈P
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 833.93 g/mol

N4-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite

CAS: 102212-98-6

Applications N4-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and …

• Formula: C₄₆H₅₂N₅O₈P
• Color and Shape: Neat
• Molecular weight: 833.91