CAS 1022282-98-9

Formula: C20H17NO4

InChI: InChI=1S/C20H17NO4/c1-21(2)14-10-7-13(8-11-14)9-12-16(22)18-19(23)15-5-3-4-6-17(15)25-20(18)24/h3-12,23H,1-2H3/b12-9+

InChI key: RGEZPZWWPVZCIT-FMIVXFBMSA-N

SMILES: CN(C)C1=CC=C(C=C1)/C=C/C(=O)C2=C(C3=CC=CC=C3OC2=O)O

LM-021

CAS: 1022282-98-9

LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1β, IL-6, and TNF-α, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.

Formula: C₂₀H₁₇NO₄

Molecular weight: 335.3533

Ref: TM-T209331