CAS 1023650-66-9

Formula: C24H22ClN3O2

InChI: InChI=1S/C24H22ClN3O2/c25-21-12-18(8-5-17(21)13-26)28-23(14-3-1-2-4-14)20-10-6-15-11-16(24(29)30)7-9-19(15)22(20)27-28/h5,7-9,11-12,14,20,23H,1-4,6,10H2,(H,29,30)/t20-,23-/m0/s1

InChI key: XNULRSOGWPFPBL-REWPJTCUSA-N

SMILES: C1CCC(C1)[C@H]2[C@H]3CCC4=C(C3=NN2C5=CC(=C(C=C5)C#N)Cl)C=CC(=C4)C(=O)O

PF-3882845

CAS: 1023650-66-9

PF-3882845

Formula: C₂₄H₂₂ClN₃O₂

Purity: ≥98%

Molecular weight: 419.9

Ref: 54-BUP01825

PF-3882845

CAS: 1023650-66-9

Purity: 99.63%

Ref: IN-DA021O55

PF-03882845

CAS: 1023650-66-9

PF-03882845 is a selective small molecule inhibitor of Janus kinase 3 (JAK3), which is derived from a pharmaceutical synthesis process. Its mode of action involves targeting and inhibiting the JAK3 enzyme, a crucial component of the JAK-STAT signaling pathway, which is integral to immune system function and various cellular processes. By specifically inhibiting JAK3, PF-03882845 interferes with the signaling pathways that rely on this kinase, potentially modulating immune responses.

Formula: C₂₄H₂₂ClN₃O₂

Purity: Min. 95%

Molecular weight: 419.9 g/mol

Ref: 3D-YQB65066

PF-3882845

CAS: 1023650-66-9

PF-3882845, a high affinity MR antagonist (IC50=2.7 nM) for hypertension, also targets progesterone receptor (IC50: 310 nM).

Formula: C₂₄H₂₂ClN₃O₂

Purity: 99.63%

Color and Shape: Solid

Molecular weight: 419.9

Ref: TM-T16502