CAS 102507-13-1

N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID

Description:

N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID, with the CAS number 102507-13-1, is a chiral amino acid derivative characterized by the presence of a tert-butyloxycarbonyl (BOC) protecting group on the amino group. This compound features a hydroxyl group and a branched aliphatic side chain, which contributes to its unique stereochemistry and potential biological activity. The BOC group is commonly used in peptide synthesis as a protective group, allowing for selective reactions without interfering with the amino functionality. The presence of the hydroxyl group enhances its solubility in polar solvents and may influence its reactivity in various chemical reactions. This compound is of interest in the fields of medicinal chemistry and biochemistry, particularly for its potential applications in drug development and peptide synthesis. Its chirality, stemming from the specific configuration of the amino acid, is crucial for its biological interactions, making it a valuable building block in the synthesis of biologically active molecules.

Formula: C₁₀H₁₉NO₅

InChI: InChI=1/C10H19NO5/c1-9(2,3)16-8(14)11-6(7(12)13)10(4,5)15/h6,15H,1-5H3,(H,11,14)(H,12,13)/t6-/m1/s1

InChI key: SZVRVSZFEDIMFM-ZCFIWIBFSA-N

SMILES: CC(C)(C)OC(=N[C@H](C(=O)O)C(C)(C)O)O

Synonyms:

• (S)-N-Alpha-T-Butyloxycarbonyl-3,3-Dimethyl-Serine
• (S)-2-Boc-Amino-3-Hydroxy-3-Methylbutyric Acid
• Boc-S-Ser(3,3Me2)-Oh
• Boc-(S)-2-Amino-3-Hydroxy-3-Methylbutanoic Acid
• Boc-L-Ser(3,3-Dimethyl)
• (S)-2-N-Boc-Amino-3-Hydroxy-3-Methylbutyric Acid
• N-(tert-butoxycarbonyl)-3-hydroxy-L-valine

N-Boc-3-hydroxy-L-valine, 97%

CAS: 102507-13-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₉NO₅

Purity: 97%

Molecular weight: 233.26

Ref: 02-H52429

3-Hydroxy-L-valine, N-BOC protected

CAS: 102507-13-1

3-Hydroxy-L-valine, N-BOC protected

Formula: C₁₀H₁₉NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 233.26155

Ref: 54-OR307092

(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid

CAS: 102507-13-1

Formula: C₁₀H₁₉NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 233.2616

Ref: IN-DA0007M6

(S)-2-N-Boc-amino-3-hydroxy-3-methylbutyric acid

CAS: 102507-13-1

Formula: C₁₀H₁₉NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 233.264

Ref: 10-F037095

Boc-Val(3-OH)-OH

CAS: 102507-13-1

(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid

Formula: C₁₀H₁₉NO₅

Purity: 97%

Molecular weight: 233.26

Ref: IN-DG12399

N-Boc-3-hydroxy-L-valine

Controlled Product

CAS: 102507-13-1

Applications N-Boc-3-hydroxy-L-valine is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir (B674500); an NS3 serine protease inhibitor of hepatitis C virus for the treatment of HCV infection.
References Arico-Muendel, C.C., et al.: Drug Metab. Dispos., 41, 814 (2013); Venkatraman, S., et al.: J. Med. Chem., 49, 6074 (2006)

Formula: C₁₀H₁₉NO₅

Color and Shape: Neat

Molecular weight: 233.26

Ref: TR-B619270

N-Boc-3-hydroxy-L-valine

CAS: 102507-13-1

Formula: C₁₀H₁₉NO₅

Molecular weight: 233.26

Ref: ST-EA-CP-B204002