CAS 1025720-94-8

Formula: C25H19ClF2N4O4

InChI: InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)

InChI key: VNBRGSXVFBYQNN-UHFFFAOYSA-N

SMILES: CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F

BMS 777607

CAS: 1025720-94-8

BMS 777607

Formula: C₂₅H₁₉ClF₂N₄O₄

Purity: 99.5%

Molecular weight: 512.89

Ref: 54-BUP12355

BMS 777607

CAS: 1025720-94-8

BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.

Formula: C₂₅H₁₉ClF₂N₄O₄

Purity: 98.89% - >99.99%

Color and Shape: Solid

Molecular weight: 512.893

Ref: TM-T2699

BMS 777607

CAS: 1025720-94-8

N-(4-((2-Amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

Formula: C₂₅H₁₉ClF₂N₄O₄

Purity: 98%

Molecular weight: 512.89

Ref: IN-DG239485

BMS 777607

CAS: 1025720-94-8

A potent Met kinase inhibitor (IC50 = 3.9 nM). Also inhibits Axl, Ron, and Tyro-3 (IC50 = 1.1, 1.8 and 4.3 nM, respectively). Anti-proliferative in Met-driven tumors in vitro and in vivo. Induces polyploidy in breast cancer cells and thereby chemoresistance.

Formula: C₂₅H₁₉ClF₂N₄O₄

Purity: Min. 95%

Molecular weight: 512.10629

Ref: 3D-FB64961

3-Pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-

CAS: 1025720-94-8

Formula: C₂₅H₁₉ClF₂N₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 512.8926

Ref: IN-DA0007S5