CAS 102577-03-7

Fengycin

Description:

Fengycin is a lipopeptide antibiotic produced by certain strains of the bacterium Bacillus subtilis. It is primarily known for its antimicrobial properties, particularly against Gram-positive bacteria and some fungi. The structure of Fengycin consists of a cyclic peptide linked to a fatty acid tail, which contributes to its membrane-disrupting activity. This amphiphilic nature allows Fengycin to interact with lipid membranes, leading to cell lysis in susceptible organisms. Fengycin is also noted for its potential applications in agriculture as a biopesticide, as it can inhibit plant pathogens. Additionally, research has indicated that Fengycin may possess anti-biofilm properties, making it a candidate for combating biofilm-associated infections. Its biosynthesis is regulated by environmental factors, and it is produced in varying amounts depending on the growth conditions of the producing strain. Overall, Fengycin represents a significant area of interest in both microbiology and biotechnology due to its unique properties and potential applications.

Formula: Unspecified

InChI: InChI=1/C72H110N12O20/c1-6-8-9-10-11-12-13-14-15-16-17-20-48(87)41-58(89)76-51(32-35-59(90)91)65(96)77-50(21-18-37-73)64(95)80-55-40-46-25-29-49(30-26-46)104-72(103)61(42(3)7-2)82-67(98)54(39-45-23-27-47(86)28-24-45)81-66(97)52(31-34-57(74)88)78-69(100)56-22-19-38-84(56)71(102)43(4)75-63(94)53(33-36-60(92)93)79-70(101)62(44(5)85)83-68(55)99/h23-30,42-44,48,50-56,61-62,85-87H,6-22,31-41,73H2,1-5H3,(H2,74,88)(H,75,94)(H,76,89)(H,77,96)(H,78,100)(H,79,101)(H,80,95)(H,81,97)(H,82,98)(H,83,99)(H,90,91)(H,92,93)/t42-,43-,44+,48?,50-,51+,52+,53+,54+,55+,56+,61+,62+/m1/s1

InChI key: CUOJDWBMJMRDHN-RLLVTFBRSA-N

SMILES: CCCCCCCCCCCCCC(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](CCCN)C(=O)N[C@@H]1CC2=CC=C(C=C2)OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@H](C)O)CCC(=O)O)C)CCC(=O)N)CC4=CC=C(C=C4)O)[C@H](C)CC)O

Synonyms:

• Fengymycin
• N-(3-hydroxyhexadecanoyl)-L-alpha-glutamyl-N-{(3S,6S,9S,17R,20S,23S,26R,31aS)-3-(3-amino-3-oxopropyl)-9-[(2R)-butan-2-yl]-23-(2-carboxyethyl)-6-(4-hydroxybenzyl)-20-[(1S)-1-hydroxyethyl]-26-methyl-1,4,7,10,18,21,24,27-octaoxo-1,2,3,4,5,6,7,8,9,10,16,17,18,19,20,21,22,23,24,25,26,27,29,30,31,31a-hexacosahydro-12,15-ethenopyrrolo[2,1-l][1,4,7,10,13,16,19,22]oxaheptaazacyclononacosin-17-yl}-D-ornithinamide
• Fengycin

Fengycin

CAS: 102577-03-7

Fengycin

Formula: C₇₂H₁₁₀N₁₂O₂₀

Purity: ≥95%

Molecular weight: 1463.71

Ref: 54-OR1124296

Fengycin

CAS: 102577-03-7

Formula: C₇₂H₁₁₀N₁₂O₂₀

Purity: 95%

Color and Shape: Solid

Molecular weight: 1463.7122

Ref: IN-DA009OQU

Fengycin

CAS: 102577-03-7

Fengycin (fengmycin), a cyclic lipopeptide produced by Bacillus subtilis, is a biosurfactant with antifungal and biodegradable properties.

Formula: C₇₂H₁₁₀N₁₂O₂₀

Color and Shape: White Viscous

Molecular weight: 1463.71

Ref: TM-T37876

Fengycin

CAS: 102577-03-7

Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.

Formula: C₇₂H₁₁₀N₁₂O₂₀

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 1,463.71 g/mol

Ref: 3D-AF35268