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Lifitegrast

CAS 1025967-78-5: Lifitegrast

Description:Lifitegrast is a synthetic small molecule classified as a lymphocyte function-associated antigen-1 (LFA-1) antagonist. It is primarily used in the treatment of dry eye disease, a condition characterized by insufficient tear production and inflammation of the ocular surface. Lifitegrast works by inhibiting the interaction between LFA-1 on lymphocytes and intercellular adhesion molecule-1 (ICAM-1) on epithelial cells, thereby reducing inflammation and promoting ocular surface health. The substance is typically administered as an eye drop solution, allowing for localized action with minimal systemic absorption. Lifitegrast has been shown to improve symptoms of dry eye and enhance tear production in clinical studies. Its safety profile includes common side effects such as eye irritation and discomfort, but it is generally well-tolerated. As a relatively novel therapeutic agent, Lifitegrast represents a targeted approach to managing dry eye disease, addressing both symptoms and underlying inflammation.

Formula:C29H24Cl2N2O7S

InChI:InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1

InChI key:InChIKey=JFOZKMSJYSPYLN-QHCPKHFHSA-N

SMILES:O=C(O)C(NC(=O)C1=C(Cl)C=C2C(=C1Cl)CCN(C(=O)C=3C=CC=4C=COC4C3)C2)CC5=CC=CC(=C5)S(=O)(=O)C

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Found 7 products.

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Ref: IN-DA0007UU

1g261.00 €
5gTo inquire
25mg53.00 €
50mg65.00 €
100mg108.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Ref: 4Z-L-153002

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Lifitegrast

CAS:1025967-78-5

Ref: 4Z-L-153001

5mg309.00 €
10mg496.00 €
25mg709.00 €
50mg881.00 €
100mg1,288.00 €
Estimated delivery in United States, on Thursday 6 Mar 2025
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Lifitegrast

CAS:1025967-78-5

Ref: TM-T3977

5mg39.00 €
10mg57.00 €
25mg92.00 €
50mg144.00 €
100mg227.00 €
500mg558.00 €
1mL*10mM (DMSO)60.00 €
Estimated delivery in United States, on Wednesday 12 Mar 2025
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Lifitegrast

Controlled Product
CAS:1025967-78-5

Ref: TR-L465955

5mg105.00 €
10mg133.00 €
250mg917.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Lifitegrast

CAS:1025967-78-5

Ref: 3D-FB146398

10mg273.00 €
50mg502.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Lifitegrast-d4

Controlled Product
CAS:1025967-78-5

Ref: TR-L465957

75mg19,315.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
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