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CAS 102691-36-1

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2-cyanoethyl N,N,N',N'-tetraisopropyl-phosphordiamidite

Description:
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite is a chemical compound commonly used in the field of organic chemistry, particularly in the synthesis of oligonucleotides. It is characterized by its phosphoramidite structure, which features a phosphorus atom bonded to two isopropyl groups and a cyanoethyl group, along with two nitrogen atoms from the amidite functional groups. This compound is typically a colorless to pale yellow liquid and is known for its stability under anhydrous conditions, making it suitable for use in nucleic acid synthesis. Its reactivity is primarily attributed to the phosphoramidite moiety, which can be activated for coupling reactions with nucleosides. The presence of the cyanoethyl group enhances the solubility and reactivity of the compound, facilitating its role as a building block in the formation of phosphodiester bonds. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.
Formula:C15H32N3OP
InChI:InChI=1/C15H32N3P/c1-12(2)17(13(3)4)19(11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3
InChI key:InChIKey=RKVHNYJPIXOHRW-UHFFFAOYSA-N
SMILES:P(N(C(C)C)C(C)C)(N(C(C)C)C(C)C)OCCC#N
Synonyms:
  • (2-Cyanoethoxy)bis(diisopropylamino)phosphine
  • 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine
  • 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
  • 2-Cyanoethyl N,N,N,N-tetraisopropyl phosphoramidite
  • 2-Cyanoethyl N,N,N,N-tetraisopropylphosphorodiamitide
  • 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
  • 2-Cyanoethyl tetraisopropylphosphorodiamidite
  • 2-Cyanoethyl-N,N,N<sup>1</sup>,N<sup>1</sup>-tetraisopropylphosphorodiamidite
  • 2-Cyanoethyltetraisopropylphosphorodiamidite
  • 2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
  • See more synonyms
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