CAS 102691-36-1

2-cyanoethyl N,N,N',N'-tetraisopropyl-phosphordiamidite

Description:

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite is a chemical compound commonly used in the field of organic chemistry, particularly in the synthesis of oligonucleotides. It is characterized by its phosphoramidite structure, which features a phosphorus atom bonded to two isopropyl groups and a cyanoethyl group, along with two nitrogen atoms from the amidite functional groups. This compound is typically a colorless to pale yellow liquid and is known for its stability under anhydrous conditions, making it suitable for use in nucleic acid synthesis. Its reactivity is primarily attributed to the phosphoramidite moiety, which can be activated for coupling reactions with nucleosides. The presence of the cyanoethyl group enhances the solubility and reactivity of the compound, facilitating its role as a building block in the formation of phosphodiester bonds. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₁₅H₃₂N₃OP

InChI: InChI=1/C15H32N3P/c1-12(2)17(13(3)4)19(11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

InChI key: InChIKey=RKVHNYJPIXOHRW-UHFFFAOYSA-N

SMILES: P(N(C(C)C)C(C)C)(N(C(C)C)C(C)C)OCCC#N

Synonyms:

• (2-Cyanoethoxy)bis(diisopropylamino)phosphine
• 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine
• 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
• 2-Cyanoethyl N,N,N,N-tetraisopropyl phosphoramidite
• 2-Cyanoethyl N,N,N,N-tetraisopropylphosphorodiamitide
• 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
• 2-Cyanoethyl tetraisopropylphosphorodiamidite
• 2-Cyanoethyl-N,N,N¹,N¹-tetraisopropylphosphorodiamidite
• 2-Cyanoethyltetraisopropylphosphorodiamidite
• 2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
• 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
• 3-([Bis[bis(propan-2-yl)amino]phosphanyl]oxy)propanenitrile
• 3-Bis(diisopropylamino)phosphanyloxypropanenitrile
• 3-Bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
• 3-[Bis(diisopropylamino) phosphinooxy]propanenitrile
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine
• Bis(diisopropylamino)-2-cyanoethoxyphosphane
• P-(2-cyanoethyl)-N,N,N',N'-tetrapropan-2-ylphosphonous diamide
• Phosphorodiamidous acid, N,N,N′,N′-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• β-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N′,N′-tetraisopropyldiamidophosphite
• 2-CYANOETHYL-N,N,N'',N''-TETRAISO-PROPYLPHOSPHORAMIDITE(P-REAGENT)
• 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite 98%
• TETRAISOPROPYLPHOSPHORODIAMIDITE
• 5) 2-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N`,N`-tertraisopropylphosphorodia
• P-REAGENT
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine P-Reagent

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

Formula: (CH₃)₂CHNPOCH₂CH₂CN

Purity: min. 98%

Color and Shape: colorless liq.

Molecular weight: 301.41

Ref: 08-15-0695

Phosphorodiamidous acid, N,N,N',N'-tetrakis(1-methylethyl)-, 2-cyanoethyl ester

CAS: 102691-36-1

Formula: C₁₅H₃₂N₃OP

Purity: 95%

Color and Shape: Solid

Molecular weight: 301.4078

Ref: IN-DA00084L

2-Cyanoethyl-N,N,N'',N''-tetraisopropylphosphordiamidite (P-Reagent)

CAS: 102691-36-1

Formula: C₁₅H₃₂N₃OP

Purity: (GC) ≥ 94.0%

Color and Shape: Colourless to light yellow liquid

Molecular weight: 301.41

Ref: 7W-GE1115

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

Formula: C₁₅H₃₂N₃OP

Purity: 93%

Color and Shape: clear. almost colourless liquid

Molecular weight: 301.41g/mol

Ref: 54-OR5367

2-Cyanoethyl N,N,N',N'-Tetraisopropylphosphordiamidite

CAS: 102691-36-1

Formula: C₁₅H₃₂N₃OP

Purity: >95.0%(GC)(T)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 301.41

Ref: 3B-C2228

3-((Bis(diisopropylamino)phosphino)oxy)-propanenitrile

CAS: 102691-36-1

Purity: 90.0%

Color and Shape: Liquid

Molecular weight: 301.4150085449219

Ref: 10-F213122

2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite

Controlled Product

CAS: 102691-36-1

Stability Explodes When Heated
Applications 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite (cas# 102691-36-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₁₅H₃₂N₃OP

Color and Shape: Neat

Molecular weight: 301.41

Ref: TR-C982100

1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11

Controlled Product

CAS: 102691-36-1

Applications 1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11 is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)

Formula: C₁₅D₁₁H₈NO₂

Color and Shape: Neat

Molecular weight: 256.385

Ref: TR-C982102

2-Cyanoethyl tetraisopropylphosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl tetraisopropylphosphorodiamidite is widely used for the preparation of modified and unmodified nucleoside phosphoramidites. Nucleoside phosphoramidites are attractive reagents for polymer-supported synthesis of oligonucleotides. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on a protected nucleoside.

Formula: C₁₅H₃₂N₃OP

Purity: (%) Min. 95.0%

Color and Shape: Colorless Slightly Yellow Clear Liquid

Molecular weight: 301.42 g/mol

Ref: 3D-FC03165

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a chemical reagent that can be used to synthesize peptides with an amine group at the C-terminus. It reacts with amino acids in aqueous solution to form peptide bonds. This product is suitable for research purposes, and has been widely used in studies of ion channels and protein interactions. 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is also used as an inhibitor in pharmacology research and can be applied to receptor or ligand binding studies.

Formula: C₁₅H₃₂N₃OP

Purity: Min. 95 Area-%

Molecular weight: 301.42 g/mol

Ref: 3D-J-509207