CAS 102691-36-1
:2-cyanoethyl N,N,N',N'-tetraisopropyl-phosphordiamidite
Description:
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite is a chemical compound commonly used in the field of organic chemistry, particularly in the synthesis of oligonucleotides. It is characterized by its phosphoramidite structure, which features a phosphorus atom bonded to two isopropyl groups and a cyanoethyl group, along with two nitrogen atoms from the amidite functional groups. This compound is typically a colorless to pale yellow liquid and is known for its stability under anhydrous conditions, making it suitable for use in nucleic acid synthesis. Its reactivity is primarily attributed to the phosphoramidite moiety, which can be activated for coupling reactions with nucleosides. The presence of the cyanoethyl group enhances the solubility and reactivity of the compound, facilitating its role as a building block in the formation of phosphodiester bonds. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.
Formula:C15H32N3OP
InChI:InChI=1/C15H32N3P/c1-12(2)17(13(3)4)19(11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3
InChI key:InChIKey=RKVHNYJPIXOHRW-UHFFFAOYSA-N
SMILES:P(N(C(C)C)C(C)C)(N(C(C)C)C(C)C)OCCC#N
Synonyms:- (2-Cyanoethoxy)bis(diisopropylamino)phosphine
- 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine
- 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
- 2-Cyanoethyl N,N,N,N-tetraisopropyl phosphoramidite
- 2-Cyanoethyl N,N,N,N-tetraisopropylphosphorodiamitide
- 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
- 2-Cyanoethyl tetraisopropylphosphorodiamidite
- 2-Cyanoethyl-N,N,N<sup>1</sup>,N<sup>1</sup>-tetraisopropylphosphorodiamidite
- 2-Cyanoethyltetraisopropylphosphorodiamidite
- 2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
- 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
- 3-([Bis[bis(propan-2-yl)amino]phosphanyl]oxy)propanenitrile
- 3-Bis(diisopropylamino)phosphanyloxypropanenitrile
- 3-Bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
- 3-[Bis(diisopropylamino) phosphinooxy]propanenitrile
- Bis(diisopropylamino)(2-cyanoethoxy)phosphine
- Bis(diisopropylamino)-2-cyanoethoxyphosphane
- P-(2-cyanoethyl)-N,N,N',N'-tetrapropan-2-ylphosphonous diamide
- Phosphorodiamidous acid, N,N,N′,N′-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
- Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
- β-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
- β-Cyanoethyl-N,N,N′,N′-tetraisopropyldiamidophosphite
- 2-CYANOETHYL-N,N,N'',N''-TETRAISO-PROPYLPHOSPHORAMIDITE(P-REAGENT)
- 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite 98%
- TETRAISOPROPYLPHOSPHORODIAMIDITE
- 5) 2-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
- β-Cyanoethyl-N,N,N`,N`-tertraisopropylphosphorodia
- P-REAGENT
- Bis(diisopropylamino)(2-cyanoethoxy)phosphine P-Reagent
- See more synonyms
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2-Cyanoethyl N,N,N',N'-Tetraisopropylphosphordiamidite
CAS:Formula:C15H32N3OPPurity:>95.0%(GC)(T)Color and Shape:Colorless to Light orange to Yellow clear liquidMolecular weight:301.412-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%
CAS:2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%
Formula:(CH3)2CHNPOCH2CH2CNPurity:min. 98%Color and Shape:colorless liq.Molecular weight:301.412-Cyanoethyl-N,N,N'',N''-tetraisopropylphosphordiamidite (P-Reagent)
CAS:Formula:C15H32N3OPPurity:(GC) ≥ 94.0%Color and Shape:Colourless to light yellow liquidMolecular weight:301.412-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite
CAS:2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamiditeFormula:C15H32N3OPPurity:93%Color and Shape:Colourless to pale yellow. Liquid-ViscousMolecular weight:301.40784Bis(diisopropylamino)(2-cyanoethoxy)phosphine
CAS:Formula:C15H32N3OPPurity:98%Color and Shape:LiquidMolecular weight:301.40782-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite
CAS:Controlled ProductStability Explodes When Heated
Applications 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite (cas# 102691-36-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C15H32N3OPColor and Shape:NeatMolecular weight:301.413-((Bis(diisopropylamino)phosphino)oxy)-propanenitrile
CAS:Formula:C15H32N3OPPurity:90.0%Color and Shape:LiquidMolecular weight:301.4152-Cyanoethyl tetraisopropylphosphorodiamidite
CAS:2-Cyanoethyl tetraisopropylphosphorodiamidite is widely used for the preparation of modified and unmodified nucleoside phosphoramidites. Nucleoside phosphoramidites are attractive reagents for polymer-supported synthesis of oligonucleotides. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on a protected nucleoside.Formula:C15H32N3OPPurity:(%) Min. 95.0%Color and Shape:Colorless Slightly Yellow Clear LiquidMolecular weight:301.42 g/mol2-Cyanoethyl N,N,N′,N′-Tetraisopropylphosphoramidite
CAS:3-((Bis(diisopropylamino)phosphino)oxy)propanenitrileFormula:C15H32N3OPPurity:97%Molecular weight:301.411-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11
CAS:Controlled ProductApplications 1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11 is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)Formula:C15D11H8NO2Color and Shape:NeatMolecular weight:256.385
