CAS 102805-45-8

(D-P-cl-phe6,leu17)-vasoactive*intestinal peptide

Formula: C₁₄₈H₂₃₉ClN₄₄O₄₂

Synonyms:

• (p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)
• H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
• [D-P-Cl-Phe(6),Leu(17)]-Vasoactive Intestinal Peptide Human, Porcine, Rat

[D-p-Cl-Phe6,Leu17]-VIP

CAS: 102805-45-8

Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.

Formula: C₁₄₈H₂₃₉ClN₄₄O₄₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 3342.24

Ref: TM-TP2103

(p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt

CAS: 102805-45-8

VIP is a potent vasoactive neuropeptide that is found in the heart, brain, and gut. It has been shown to be a potent inhibitor of guanethidine-induced contractions in the femoral vein, as well as atrial contractions. VIP also inhibits spontaneous contractions in the fundic region of the stomach and intestinal motility. VIP has been shown to inhibit vasoactive intestinal polypeptide-induced contractions in isolated rat ileum. VIP is expressed primarily in the enteric nervous system and throughout the gastrointestinal tract.

Formula: C₁₄₈H₂₃₉ClN₄₄O₄₂

Purity: Min. 95%

Molecular weight: 3,342.21 g/mol

Ref: 3D-FC109522