CAS 103-80-0

Phenylacetyl chloride

Description:

Phenylacetyl chloride, with the CAS number 103-80-0, is an organic compound characterized by its acyl chloride functional group. It appears as a colorless to pale yellow liquid with a pungent odor, typical of acyl chlorides. This compound is known for its reactivity, particularly in nucleophilic acyl substitution reactions, where it can react with alcohols, amines, and other nucleophiles to form esters, amides, and other derivatives. Phenylacetyl chloride is soluble in organic solvents such as dichloromethane and ether but is not soluble in water due to its hydrophobic nature. It is primarily used in organic synthesis, particularly in the preparation of phenylacetyl derivatives and as an intermediate in the production of pharmaceuticals and agrochemicals. Due to its reactive nature, it must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment and working in a well-ventilated area or fume hood, are essential when working with this compound.

Formula: C₈H₇ClO

InChI: InChI=1/C8H7ClO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2

InChI key: InChIKey=VMZCDNSFRSVYKQ-UHFFFAOYSA-N

SMILES: C(C(Cl)=O)C1=CC=CC=C1

Synonyms:

• 2-Phenylacetic acid chloride
• 2-Phenylacetyl chloride
• 2-Phenylethanoyl chloride
• Acetyl chloride, phenyl-
• Chlorure De Phenylacetyle
• Cloruro De Fenilacetilo
• Phenacetyl chloride
• Phenylacetic acid chloride
• Phenylacetic chloride
• Phenylacetyl Chloride
• Phenylacetylchlorid
• α-Phenylacetyl chloride
• Benzeneacetyl chloride
• Phenylacethylchloride
• Phenyl acetyl chloride
• PHENYL ACETY1[E] CHLORIDE
• phenylacetyl
• alpha-Phenylacetyl chloride
• -Toluylchloride
• A-TOLUYL CHLORIDE
• alpha-Toluyl chloride
• AKOS BBS-00003909

Phenylacetyl Chloride

CAS: 103-80-0

Formula: C₈H₇ClO

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 154.59

Ref: 3B-P0129

Phenylacetyl chloride, 98%

CAS: 103-80-0

Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in

Formula: C₈H₇ClO

Purity: 98%

Color and Shape: Liquid, Clear colorless to yellow or pink-red

Molecular weight: 154.59

Ref: 02-B24987

Phenylacetyl chloride

CAS: 103-80-0

Formula: C₈H₇ClO

Purity: ≥ 99.0%

Color and Shape: Light yellow liquid

Molecular weight: 154.60

Ref: 7W-GK2112

Phenylacetyl chloride

CAS: 103-80-0

Phenylacetyl chloride

Purity: 95%

Molecular weight: 154.59g/mol

Ref: 54-OR2206

Phenylacetyl Chloride(Benzeneacetyl Chloride)

Controlled Product

CAS: 103-80-0

Stability Moisture Sensitive
Applications Benzeneacetyl Chloride is used in the synthesis of aromatic inhibitors of HIV-1 integrase. Also used in the preparation of napthalenic ligands with high affinity for melatonin receptor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Burke, T. et al.: J. Med. Chem., 38, 4171 (1995); Yous, S. et al.: J. Med. Chem., 35, 1484 (1992);

Formula: C₈H₇ClO

Color and Shape: Neat

Molecular weight: 154.59

Ref: TR-B188800

Phenyl acetyl chloride

Controlled Product

CAS: 103-80-0

Phenyl acetyl chloride (PA) is an antibiotic-resistant agent that inhibits the enzyme matrix metalloproteinase. It has been shown to be effective against bowel disease, such as inflammatory bowel disease, and also has potent antitumor activity. PA binds to a protein called p-hydroxybenzoic acid (PHBA), which is a receptor for PA in the stomach lining. The PHBA receptor is responsible for the matrix effect, which destroys bacteria by breaking down the connective tissue in the mucosal lining of the gut. PA also inhibits tumor growth by preventing cell proliferation and inducing apoptosis.

Formula: C₈H₇ClO

Purity: Min. 95%

Molecular weight: 154.59 g/mol

Ref: 3D-FP02656