CAS 103-80-0: Phenylacetyl chloride
Description:Phenylacetyl chloride, with the CAS number 103-80-0, is an organic compound characterized by its acyl chloride functional group. It appears as a colorless to pale yellow liquid with a pungent odor, typical of acyl chlorides. This compound is known for its reactivity, particularly in nucleophilic acyl substitution reactions, where it can react with alcohols, amines, and other nucleophiles to form esters, amides, and other derivatives. Phenylacetyl chloride is soluble in organic solvents such as dichloromethane and ether but is not soluble in water due to its hydrophobic nature. It is primarily used in organic synthesis, particularly in the preparation of phenylacetyl derivatives and as an intermediate in the production of pharmaceuticals and agrochemicals. Due to its reactive nature, it must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment and working in a well-ventilated area or fume hood, are essential when working with this compound.
Formula:C8H7ClO
InChI:InChI=1S/C8H7ClO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2
InChI key:InChIKey=VMZCDNSFRSVYKQ-UHFFFAOYSA-N
SMILES:O=C(Cl)CC=1C=CC=CC1
- Synonyms:
- 2-Phenylacetic acid chloride
- 2-Phenylacetyl chloride
- 2-Phenylethanoyl chloride
- Acetyl chloride, phenyl-
- Chlorure De Phenylacetyle
- Cloruro De Fenilacetilo
- Phenacetyl chloride
- Phenylacetic acid chloride
- Phenylacetic chloride
- Phenylacetyl Chloride
- See more synonyms
- Phenylacetylchlorid
- α-Phenylacetyl chloride
- Benzeneacetyl chloride
- Phenylacethylchloride
- Phenyl acetyl chloride
- PHENYL ACETY1[E] CHLORIDE
- phenylacetyl
- alpha-Phenylacetyl chloride
- -Toluylchloride
- A-TOLUYL CHLORIDE
- alpha-Toluyl chloride
- AKOS BBS-00003909
- LABOTEST-BB LT00643802
