CAS 1032350-13-2: MK 2206 dihydrochloride

Description: MK 2206 dihydrochloride is a small molecule inhibitor that primarily targets the protein kinase AKT, which plays a crucial role in various cellular processes, including metabolism, proliferation, and survival. This compound is often studied in the context of cancer research due to its potential to inhibit tumor growth and enhance the efficacy of other therapeutic agents. MK 2206 dihydrochloride is characterized by its solubility in water, which facilitates its use in biological assays. The compound typically exhibits a moderate to high affinity for AKT, leading to the disruption of downstream signaling pathways associated with cell survival and growth. Its chemical structure includes a specific arrangement of functional groups that contribute to its biological activity. In preclinical studies, MK 2206 has shown promise in various cancer models, making it a candidate for further investigation in clinical settings. However, like many investigational drugs, its safety and efficacy in humans are subjects of ongoing research.

Formula: C₂₅H₂₁N₅O·2ClH

InChI: InChI=1S/C25H21N5O.2ClH/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31;;/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31);2*1H

InChI key: InChIKey=HWUHTJIKQZZBRA-UHFFFAOYSA-N

SMILES: Cl.O=C1NN=C2C=3C=C(C=4C=CC=CC4)C(=NC3C=CN12)C=5C=CC(=CC5)C6(N)CCC6

Synonyms:

• 1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-, hydrochloride (1:2)
• 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride
• MK 2206 dihydrochloride

MK-2206 2HCl

CAS: 1032350-13-2

• Formula: C₂₅H₂₃Cl₂N₅O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 480.3890

MK-2206 dihydrochloride

CAS: 1032350-13-2

• Formula: C₂₅H₂₃Cl₂N₅O
• Molecular weight: 480.39

MK-2206 dihydrochloride

CAS: 1032350-13-2

MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 …

• Formula: C₂₅H₂₃Cl₂N₅O
• Purity: 99.228% - 99.91%
• Color and Shape: Solid
• Molecular weight: 480.39

MK 2206 dihydrochloride

CAS: 1032350-13-2

MK 2206 is an allosteric inhibitor acting on the protein kinase B (AKT) signaling pathway. …

• Formula: C₂₅H₂₃Cl₂N₅O
• Purity: Min. 98 Area-%
• Color and Shape: Off-White To Yellow Solid
• Molecular weight: 480.39 g/mol

MK-2206 Dihydrochloride

CAS: 1032350-13-2

Applications AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT …

• Formula: C₂₅H₂₁N₅OClH
• Color and Shape: Neat
• Molecular weight: 480.39