CAS 1032754-81-6

Formula: C21H28N8O3S2

InChI: InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2,30)31)33-18-17(14)25-19(15-11-23-21(22)24-12-15)26-20(18)28-7-9-32-10-8-28/h11-12H,3-10,13H2,1-2H3,(H2,22,23,24)

InChI key: AKKCGLXULFRAET-UHFFFAOYSA-N

SMILES: CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)S(=O)(=O)C

GNE-477

CAS: 1032754-81-6

GNE-477

Formula: C₂₁H₂₈N₈O₃S₂

Purity: ≥98%

Molecular weight: 504.63

Ref: 54-BUP02841

5-(7-Methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

CAS: 1032754-81-6

Formula: C₂₁H₂₈N₈O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 504.6288

Ref: IN-DA008TGI

GNE-477

CAS: 1032754-81-6

Ref: 7W-GW3723

GNE-477

CAS: 1032754-81-6

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.

Formula: C₂₁H₂₈N₈O₃S₂

Purity: 98.88% - 99.55%

Color and Shape: Solid

Molecular weight: 504.629

Ref: TM-T3692

GNE-477

CAS: 1032754-81-6

5-(7-Methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

Formula: C₂₁H₂₈N₈O₃S₂

Purity: 99%

Molecular weight: 504.63

Ref: IN-DG556730

GNE-477

CAS: 1032754-81-6

GNE-477 is a small molecule with pharmacological properties that has been shown to inhibit the growth of cancer cells in vitro and in vivo. GNE-477 has been shown to inhibit autophagy, which may be responsible for its potent anticancer activity. GNE-477 also inhibits the activation of nuclear DNA and lipid kinase, inhibiting the production of proteins necessary for cell division. This drug is used to treat autoimmune diseases, skin cancer, and squamous carcinoma. GNE-477 also has anti-inflammatory properties that may be due to its inhibition of the epidermal growth factor receptor (EGFR).

Formula: C₂₁H₂₈N₈O₃S₂

Purity: Min. 95%

Molecular weight: 504.63 g/mol

Ref: 3D-HRB75481