CAS 10329-75-6

Trileucine

Description:

Trileucine, with the CAS number 10329-75-6, is a synthetic peptide composed of three leucine amino acids linked together by peptide bonds. It is classified as a branched-chain amino acid (BCAA), which is known for its role in protein synthesis and muscle metabolism. Trileucine exhibits characteristics typical of leucine, including hydrophobic properties, which contribute to its role in protein structure and function. This peptide is often studied for its potential applications in nutrition and biochemistry, particularly in relation to muscle recovery and growth. Trileucine can influence metabolic pathways and may have implications in various physiological processes. Its stability and solubility in aqueous solutions make it suitable for various experimental conditions. Additionally, trileucine can be utilized in research settings to explore peptide synthesis, structure-activity relationships, and the effects of amino acid sequences on biological activity. Overall, trileucine serves as an important model compound in the study of peptides and their functions in biological systems.

Formula: C₁₈H₃₅N₃O₄

InChI: InChI=1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)/t13-,14-,15-/m0/s1

InChI key: InChIKey=DNDWZFHLZVYOGF-KKUMJFAQSA-N

SMILES: [C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)(NC([C@H](CC(C)C)N)=O)CC(C)C

Synonyms:

• 135: PN: WO2009132287 SEQID: 171 claimed protein
• 7: PN: US20160367463 SEQID: 8 claimed protein
• 7: PN: WO2016204841 SEQID: 8 claimed protein
• 8: PN: WO2020142103 SEQID: 8 claimed protein
• <span class="text-smallcaps">L</smallcap>-Leucine, <smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucyl-
• <span class="text-smallcaps">L</smallcap>-Leucine, N-(N-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucyl)-
• <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucine
• L-Leucy-L-Leucyl-L-Leucine
• L-leucyl-L-leucyl-L-leucine
• Leucine, N-(N-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-leucyl)-, <smallcap>L</span>-
• Leucine, N-(N-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucyl)-
• Leucylleucylleucine
• Trileucine
• L-Leucine, N-(N-L-leucyl-L-leucyl)-
• Leucine, N-(N-L-leucyl-L-leucyl)-
• Leucine, N-(N-L-leucyl-L-leucyl)-, L-

H-Leu-Leu-Leu-OH

CAS: 10329-75-6

The tripeptide trileucine, found in casein and soy protein, was shown to increase the endothelial release of TXB₂, a stable marker of TXA₂. Inhibitor of human liver alanine aminopeptidase, Ki 0.054 mM. Addition of trileucine improved aerosol performance and stability of spray-dried powders for inhalation.

Formula: C₁₈H₃₅N₃O₄

Purity: > 99%

Color and Shape: White

Molecular weight: 357.49

Ref: 01-4002312

L-Leucine, L-leucyl-L-leucyl-

CAS: 10329-75-6

Formula: C₁₈H₃₅N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 357.4882

Ref: IN-DA00HA0X

(S)-2-((S)-2-((S)-2-Amino-4-Methylpentanamido)-4-Methylpentanamido)-4-Methylpentanoic Acid

CAS: 10329-75-6

(S)-2-((S)-2-((S)-2-Amino-4-Methylpentanamido)-4-Methylpentanamido)-4-Methylpentanoic Acid

Purity: 98%

Molecular weight: 357.49g/mol

Ref: 54-OR1008631

Leucyl-leucyl-leucine

CAS: 10329-75-6

Trileucine aids in pH-dependent endosomal release and HPLC media absorption testing.

Formula: C₁₈H₃₅N₃O₄

Color and Shape: Solid

Molecular weight: 357.49

Ref: TM-T20433

Leu-Leu-Leu-OH

CAS: 10329-75-6

Formula: C₁₈H₃₅N₃O₄

Purity: 98%

Molecular weight: 357.495

Ref: 10-F493125

Leu-Leu-Leu-OH

CAS: 10329-75-6

Leu-Leu-Leu-OH is a pentapeptide that is used in cancer treatment to inhibit the growth of cancer cells. It prevents the production of proteins and, as a result, cell division. Leu-Leu-Leu-OH has been shown to be effective against tumor cells with an antibody that binds to the surface of cells. The monoclonal antibody is taken up by the cancer cells through receptor mediated endocytosis, which leads to inhibition of protein synthesis and cell death.

Formula: C₁₈H₃₅N₃O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 357.49 g/mol

Ref: 3D-FL49327