CymitQuimica logo

CAS 103300-74-9

:

Taltirelin

Description:
Taltirelin, with the CAS number 103300-74-9, is a synthetic peptide that acts as a thyrotropin-releasing hormone (TRH) analog. It is primarily characterized by its ability to stimulate the release of thyroid-stimulating hormone (TSH) from the pituitary gland, thereby influencing thyroid function. Taltirelin is often studied for its potential therapeutic applications in conditions related to thyroid dysfunction and neurodegenerative diseases. The substance is typically administered via injection and has been investigated for its neuroprotective properties, particularly in models of Alzheimer's disease and other cognitive disorders. Its mechanism of action involves binding to TRH receptors, leading to a cascade of biological effects that promote neuronal health and function. Taltirelin is also noted for its relatively low toxicity profile, making it a candidate for further research in both endocrinology and neurology. As with any pharmaceutical compound, its use should be guided by clinical evidence and regulatory approval.
Formula:C17H23N7O5
InChI:InChI=1S/C17H23N7O5/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26/h7-8,10-12H,2-6H2,1H3,(H2,18,26)(H,19,20)(H,21,27)(H,22,29)/t10-,11-,12-/m0/s1
InChI key:InChIKey=LQZAIAZUDWIVPM-SRVKXCTJSA-N
SMILES:C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CC(=O)N(C)C(=O)N2)(=O)N3[C@H](C(N)=O)CCC3
Synonyms:
  • (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-<span class="text-smallcaps">L</smallcap>-histidyl-<smallcap>L</span>-prolinamide
  • (4S)-N-[(2S)-1-[(2S)-2-Carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide
  • 2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-
  • <span class="text-smallcaps">L</smallcap>-Prolinamide, (4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-<smallcap>L</span>-histidyl-
  • <span class="text-smallcaps">L</smallcap>-Prolinamide, N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-<smallcap>L</span>-histidyl-, (S)-
  • Ceredist
  • L-Prolinamide, N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-, (S)-
  • L-Prolinamide, N-[[(4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl- (9CI)
  • L-Prolinamide,(4S)-hexahydro-1-methyl-
  • N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 9 products.