CAS 103300-77-2

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline

Description:

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline, with CAS number 103300-77-2, is a complex organic compound characterized by its unique structural features that include a pyrimidine ring and amino acid components. This substance is part of a class of compounds known as peptides, which are formed by the linkage of amino acids through peptide bonds. The presence of the hexahydro structure indicates a saturated cyclic component, contributing to its stability and potential biological activity. The dioxo groups suggest that the compound may participate in various chemical reactions, possibly acting as a reactive intermediate or influencing its interaction with biological targets. Additionally, the L-histidyl and L-proline residues indicate that this compound may exhibit specific stereochemical properties, which can affect its biological function and interactions. Overall, this compound's characteristics suggest potential applications in pharmaceuticals or biochemistry, particularly in the development of therapeutic agents or as a biochemical probe.

Formula: C₁₇H₂₂N₆O₆

InChI: InChI=1S/C17H22N6O6/c1-22-13(24)6-10(21-17(22)29)14(25)20-11(5-9-7-18-8-19-9)15(26)23-4-2-3-12(23)16(27)28/h7-8,10-12H,2-6H2,1H3,(H,18,19)(H,20,25)(H,21,29)(H,27,28)/t10-,11-,12-/m0/s1

InChI key: InChIKey=ZJLMUEVCSWSNNQ-SRVKXCTJSA-N

SMILES: C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CC(=O)N(C)C(=O)N2)(=O)N3[C@H](C(O)=O)CCC3

Synonyms:

• L-Proline, (4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-
• (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline
• L-Proline, 1-[N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl]-, (S)-

TA 0910 acid-type

CAS: 103300-77-2

TA 0910 acid-type is a metabolite of TA 0910. TA-0910 is a metabolically stable analog of thyrotropin-releasing hormone.

Formula: C₁₇H₂₂N₆O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 406.39

Ref: TM-T16972

Taltirelin Impurity 1

CAS: 103300-77-2

Formula: C₁₇H₂₂N₆O₆

Molecular weight: 406.40

Ref: 4Z-T-160002

Taltirelin Impurity 1-13C-d3

CAS: 103300-77-2

Formula: C₁₆₁₃CH₁₉D₃N₆O₆

Molecular weight: 410.41

Ref: 4Z-T-160007

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline

CAS: 103300-77-2

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline is a prodrug that is metabolized by esterases in the gastrointestinal tract to form the active drug L-(3,5 dimethoxybenzyl)histidylprolinamide. This compound has been shown to inhibit thyroid hormone biosynthesis and may be useful for the treatment of thyroid disease. The compound also has neuroprotective properties and may be beneficial for the treatment of Alzheimer's disease.

Formula: C₁₇H₂₂N₆O₆

Purity: Min. 95%

Molecular weight: 406.4 g/mol

Ref: 3D-DEA30077