CAS 103300-77-2

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline

Formula: C₁₇H₂₂N₆O₆

InChI: InChI=1S/C17H22N6O6/c1-22-13(24)6-10(21-17(22)29)14(25)20-11(5-9-7-18-8-19-9)15(26)23-4-2-3-12(23)16(27)28/h7-8,10-12H,2-6H2,1H3,(H,18,19)(H,20,25)(H,21,29)(H,27,28)/t10-,11-,12-/m0/s1

InChI key: InChIKey=ZJLMUEVCSWSNNQ-SRVKXCTJSA-N

SMILES: C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CC(=O)N(C)C(=O)N2)(=O)N3[C@H](C(O)=O)CCC3

Synonyms:

• L-Proline, (4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-
• (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline
• L-Proline, 1-[N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl]-, (S)-

TA 0910 acid-type

CAS: 103300-77-2

TA 0910 acid-type

Formula: C₁₇H₂₂N₆O₆

Purity: 99.85%

Molecular weight: 406.39

Ref: 54-OR1133958

TA 0910 acid-type

CAS: 103300-77-2

TA 0910 acid-type is a metabolite of TA 0910. TA-0910 is a metabolically stable analog of thyrotropin-releasing hormone.

Formula: C₁₇H₂₂N₆O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 406.39

Ref: TM-T16972

Taltirelin Impurity 1

CAS: 103300-77-2

Formula: C₁₇H₂₂N₆O₆

Molecular weight: 406.40

Ref: 4Z-T-160002

Taltirelin Impurity 1-13C-d3

CAS: 103300-77-2

Formula: C₁₆₁₃CH₁₉D₃N₆O₆

Molecular weight: 410.41

Ref: 4Z-T-160007

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline

CAS: 103300-77-2

(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-proline is a prodrug that is metabolized by esterases in the gastrointestinal tract to form the active drug L-(3,5 dimethoxybenzyl)histidylprolinamide. This compound has been shown to inhibit thyroid hormone biosynthesis and may be useful for the treatment of thyroid disease. The compound also has neuroprotective properties and may be beneficial for the treatment of Alzheimer's disease.

Formula: C₁₇H₂₂N₆O₆

Purity: Min. 95%

Molecular weight: 406.4 g/mol

Ref: 3D-DEA30077