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CAS 103577-45-3

:

Lansoprazole

Description:
Lansoprazole is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome by reducing stomach acid production. It is a white to off-white crystalline powder that is slightly soluble in water and more soluble in organic solvents. The chemical formula of lansoprazole is C16H14F3N3O2S, and it features a benzimidazole core with a sulfinyl group and a trifluoromethyl group, contributing to its pharmacological activity. Lansoprazole is typically administered orally and is available in various formulations, including delayed-release capsules and orally disintegrating tablets. Its mechanism of action involves the irreversible inhibition of the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased gastric acid secretion. Common side effects may include headache, diarrhea, and abdominal pain, while long-term use can be associated with risks such as vitamin B12 deficiency and gastrointestinal infections. Overall, lansoprazole is an effective medication for managing acid-related disorders.
Formula:C16H14F3N3O2S
InChI:InChI=1/C17H14F3N3O2/c1-10-13(21-7-6-15(10)25-9-17(18,19)20)8-14(24)16-22-11-4-2-3-5-12(11)23-16/h2-7H,8-9H2,1H3,(H,22,23)
InChI key:InChIKey=MJIHNNLFOKEZEW-UHFFFAOYSA-N
SMILES:S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3
Synonyms:
  • (±)-Lansoprazol
  • 1-(1H-benzimidazol-2-yl)-2-[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]ethanone
  • 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
  • 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
  • 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
  • 2-[3-Methyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole
  • 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
  • 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
  • 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole
  • 2-[[[4-(2,2,2-Trifluoroethoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole
  • See more synonyms
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