CAS 103577-45-3

Lansoprazole

Description:

Lansoprazole is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome by reducing stomach acid production. It is a white to off-white crystalline powder that is slightly soluble in water and more soluble in organic solvents. The chemical formula of lansoprazole is C16H14F3N3O2S, and it features a benzimidazole core with a sulfinyl group and a trifluoromethyl group, contributing to its pharmacological activity. Lansoprazole is typically administered orally and is available in various formulations, including delayed-release capsules and orally disintegrating tablets. Its mechanism of action involves the irreversible inhibition of the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased gastric acid secretion. Common side effects may include headache, diarrhea, and abdominal pain, while long-term use can be associated with risks such as vitamin B12 deficiency and gastrointestinal infections. Overall, lansoprazole is an effective medication for managing acid-related disorders.

Formula: C₁₆H₁₄F₃N₃O₂S

InChI: InChI=1/C17H14F3N3O2/c1-10-13(21-7-6-15(10)25-9-17(18,19)20)8-14(24)16-22-11-4-2-3-5-12(11)23-16/h2-7H,8-9H2,1H3,(H,22,23)

InChI key: InChIKey=MJIHNNLFOKEZEW-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3

Synonyms:

• (±)-Lansoprazol
• 1-(1H-benzimidazol-2-yl)-2-[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]ethanone
• 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
• 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
• 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
• 2-[3-Methyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole
• 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole
• 2-[[[4-(2,2,2-Trifluoroethoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole
• 2-{[[3-methyl-4-(2,2,2-trifluoroethoxy)2-pyridinyl]methyl]sulfonyl}1H-benzimidazole
• A 65006
• Ag 1749
• Agopton
• Alter
• Cinfa
• Davur
• Ilsatec
• Ketian
• Lancid
• Lanfast
• Lanpro
• Lanproton
• Lanso
• Lansofast
• Lansopep
• Lansophed
• Lansoprazile
• Lansor
• Lansox
• Lanston
• Lanz
• Lanzo
• Lanzol
• Lanzol 30
• Lanzole
• Lanzopen
• Lanzopral
• Lanzor
• Lapraz
• Lasoprazole
• Levant
• Ogast
• Ogastro
• Pp/K-10
• Prevacid
• Promp
• Propilan
• Prosogan
• RS-lansoprazole
• Suprecid
• Takepron
• Takepron OD
• Tapepron
• Ulpax
• Zoton
• Lansoprazole
• lfinyl)-
• LANSOPRAZOLE, MM(CRM STANDARD)
• LANSOPRAZOLE USP(CRM STANDARD)
• 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1h-benzoimidazole
• 1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su
• 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz
• LANSOPRAZOLE, RELATED COMPOUND A2-[[[3-METHYL-4-(2,2,2-TRIFLOUROETHOXY)-2-PYRIDYL]METHYL]SULFONYL]BENZIMIDAZOLE USP STANDARD
• A-65006, AG-1749, Agopton, Lansox, Lanzor, Limpidex, Ogast, Prevacid,
• LANSAPRAZOLE
• LIMPIDEX

Lansoprazole

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 369.36

Ref: 3B-L0233

Lansoprazole, 98+%

CAS: 103577-45-3

A proton pump inhibitor

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 98+%

Molecular weight: 369.36

Ref: 02-J62008

LANSOPRAZOLE CRS

CAS: 103577-45-3

LANSOPRAZOLE CRS

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: White. Dark. Powder.

Molecular weight: 369.3615

Ref: 41-Y0000773

LANSOPRAZOLE FOR PEAK IDENTIFICATION CRS

CAS: 103577-45-3

LANSOPRAZOLE FOR PEAK IDENTIFICATION CRS

Formula: C₁₆H₁₄F₃N₃O₂S

Molecular weight: 369.3615

Ref: 41-Y0000774

Lansoprazole impurity standard

CAS: 103577-45-3, 131926-99-3, 213476-12-1

Lansoprazole impurity standard

Color and Shape: White To Beige

Ref: 47-873

Lansoprazole

CAS: 103577-45-3

Lansoprazole

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 99.9%

Color and Shape: White To Light Brown

Molecular weight: 369.07588

Ref: 47-872

Lansoprazole

CAS: 103577-45-3

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: White Brown Powder

Molecular weight: 369.07588

Ref: 45-1356916

1H-​Benzimidazole, 2-​[[[3-​methyl-​4-​(2,​2,​2-​trifluoroethoxy)​-​2-​pyridinyl]​methyl]​sulfinyl]​-

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.3615

Ref: IN-DA003R7E

Lansoprazole

CAS: 103577-45-3

Lansoprazole

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 369.36

Ref: 54-BUP18466

Lansoprazole

CAS: 103577-45-3

Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 99.18% - 99.84%

Color and Shape: Yellow Solid

Molecular weight: 369.36

Ref: TM-T0674

Lansoprazole

CAS: 103577-45-3

Lansoprazole

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: >98%

Molecular weight: 369.36

Ref: 54-PC109167

Lansoprazole

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 99.0 - 101.0 %

Color and Shape: White to off-white powder

Molecular weight: 369.36

Ref: 7W-GP5308

Lansoprazole

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: White To Off-White Solid

Molecular weight: 369.36

Ref: 4Z-L-031

Lansoprazole

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 369.36

Ref: 04-C14592500

Lansoprazole

Controlled Product

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 369.36

Ref: 86-MM0474.00

Lansoprazole

CAS: 103577-45-3

Color and Shape: White To Light Beige

Ref: 61-FOR0474.00

Lansoprazole (Standard)

CAS: 103577-45-3

Lansoprazole (Standard) is the standard substance of Lansoprazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Solid

Molecular weight: 369.36

Ref: TM-TMSM-1428

Lansoprazole

CAS: 103577-45-3

2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 98%

Molecular weight: 369.36

Ref: IN-DG41116

Lansoprazole

CAS: 103577-45-3

Formula: C₁₆H₁₄F₃N₃O₂S

Molecular weight: 369.36

Ref: ST-EA-CP-L11000

Lansoprazole

CAS: 103577-45-3

Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 369.36

Ref: TR-L175000