CAS 103628-46-2: Sumatriptan

Description: Sumatriptan is a medication primarily used to treat migraine headaches and cluster headaches. It belongs to a class of drugs known as triptans, which are selective agonists for serotonin receptors, specifically the 5-HT_1B and 5-HT_1D subtypes. The chemical formula of sumatriptan is C_14H_21N_3O_2S, and it has a molecular weight of approximately 295.4 g/mol. This compound is characterized by its sulfonamide group, which contributes to its pharmacological activity. Sumatriptan is typically administered in various forms, including oral tablets, nasal sprays, and injections, allowing for rapid onset of action. Its mechanism of action involves vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release, effectively alleviating migraine symptoms. Common side effects may include dizziness, drowsiness, and sensations of tingling or warmth. Due to its specific action on serotonin receptors, sumatriptan is generally contraindicated in patients with cardiovascular diseases. Overall, sumatriptan is a vital therapeutic option for managing acute migraine episodes.

Formula: C₁₄H₂₁N₃O₂S

InChI: InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3

InChI key: InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N

SMILES: O=S(=O)(NC)CC=1C=CC=2NC=C(C2C1)CCN(C)C

Synonyms:

• 1-{3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide
• 1-{3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethansulfonamid
• 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide butanedioate (1:1)
• 1H-Indole-5-methanesulfonamide, 3-(2-(dimethylamino)ethyl)-N-methyl-
• 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide
• 3-[2-(Dimethylamino)ethyl]-N-methylindolyl-5-methanesulfonamide
• Gr 43175
• Gr 43175C
• Gr 43175X
• N,N-dimethyl-2-[5-(methylaminomethylsulfonyl)-1H-indol-3-yl]ethanamine
• Onzetra Xsail
• Zecuity
• Zelrix
• Sumatriptan

Sumatriptan Succinate

CAS: 103628-46-2103628-48-4

• Formula: C₁₄H₂₁N₃O₂S·C₄H₆O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 413.49

Sumatriptan

CAS: 103628-46-2

Sulfonamides used as drugs

• Formula: C₁₄H₂₁N₃O₂S
• Color and Shape: White Off-White Powder
• Molecular weight: 295.13545

1H-Indole-5-methanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methyl-

CAS: 103628-46-2

• Formula: C₁₄H₂₁N₃O₂S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 295.4004

Sumatriptan

CAS: 103628-46-2

• Purity: 99.92%
• Molecular weight: 295.4g/mol

Sumatriptan

CAS: 103628-46-2

• Formula: C₁₄H₂₁N₃O₂S
• Molecular weight: 295.40

Sumatriptan

CAS: 103628-46-2

Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in …

• Formula: C₁₄H₂₁N₃O₂S
• Purity: 99.93%
• Color and Shape: White To Off-White Crystalline Powder
• Molecular weight: 295.4

Sumatriptan

CAS: 103628-46-2

• Formula: C₁₄H₂₁N₃O₂S
• Color and Shape: Neat
• Molecular weight: 295.40

Sumatriptan

CAS: 103628-46-2

• Formula: C₁₄H₂₁N₃O₂S
• Molecular weight: 295.41

Sumatriptan

CAS: 103628-46-2

• Purity: 98%
• Molecular weight: 295.3999938964844

Sumatriptan

CAS: 103628-46-2

Applications Sumatriptan is a serotonin 5HT1-receptor agonist. References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., …

• Formula: C₁₄H₂₁N₃O₂S
• Color and Shape: White To Light Yellow
• Molecular weight: 295.40

Sumatriptan - Bio-X ™

CAS: 103628-46-2

Sumatriptan is a serotonin receptor agonist that is used for treating migraines and cluster headaches. …

• Formula: C₁₄H₂₁N₃O₂S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 295.4 g/mol

Sumatriptan

CAS: 103628-46-2

5-HT1B/1D serotonin receptor agonist; anti-migraine agent

• Formula: C₁₄H₂₁N₃O₂S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 295.4 g/mol

1-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt

CAS: 103628-46-2

• Formula: C₂₅H₃₃N₅O₄S₂·CH₂O₂
• Color and Shape: Neat
• Molecular weight: 531.694603