CAS 103628-46-2

Sumatriptan

Description:

Sumatriptan is a medication primarily used to treat migraine headaches and cluster headaches. It belongs to a class of drugs known as triptans, which are selective agonists for serotonin receptors, specifically the 5-HT_1B and 5-HT_1D subtypes. The chemical formula of sumatriptan is C_14H_21N_3O_2S, and it has a molecular weight of approximately 295.4 g/mol. This compound is characterized by its sulfonamide group, which contributes to its pharmacological activity. Sumatriptan is typically administered in various forms, including oral tablets, nasal sprays, and injections, allowing for rapid onset of action. Its mechanism of action involves vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release, effectively alleviating migraine symptoms. Common side effects may include dizziness, drowsiness, and sensations of tingling or warmth. Due to its specific action on serotonin receptors, sumatriptan is generally contraindicated in patients with cardiovascular diseases. Overall, sumatriptan is a vital therapeutic option for managing acute migraine episodes.

Formula: C₁₄H₂₁N₃O₂S

InChI: InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3

InChI key: InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N

SMILES: C(CN(C)C)C=1C=2C(NC1)=CC=C(CS(NC)(=O)=O)C2

Synonyms:

• 1-{3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide
• 1-{3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethansulfonamid
• 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide butanedioate (1:1)
• 1H-Indole-5-methanesulfonamide, 3-(2-(dimethylamino)ethyl)-N-methyl-
• 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide
• 3-[2-(Dimethylamino)ethyl]-N-methylindolyl-5-methanesulfonamide
• Gr 43175
• Gr 43175C
• Gr 43175X
• N,N-dimethyl-2-[5-(methylaminomethylsulfonyl)-1H-indol-3-yl]ethanamine
• Onzetra Xsail
• Zecuity
• Zelrix

Sumatriptan Succinate

CAS: 103628-46-2, 103628-48-4

Formula: C₁₄H₂₁N₃O₂S·C₄H₆O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 413.49

Ref: 3B-S0851

Sumatriptan

CAS: 103628-46-2

Sulfonamides used as drugs

Formula: C₁₄H₂₁N₃O₂S

Color and Shape: White Off-White Powder

Molecular weight: 295.13545

Ref: 45-1642154

Sumatriptan

CAS: 103628-46-2

Sumatriptan

Formula: C₁₄H₂₁N₃O₂S

Purity: ≥98%

Molecular weight: 295.4

Ref: 54-BUP13657

1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide

CAS: 103628-46-2

Formula: C₁₄H₂₁N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 295.4004

Ref: IN-DA01CCKD

Sumatriptan

CAS: 103628-46-2

Formula: C₁₄H₂₁N₃O₂S

Molecular weight: 295.40

Ref: 7W-GP3922

Sumatriptan

CAS: 103628-46-2

Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.

Formula: C₁₄H₂₁N₃O₂S

Purity: 99.93%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 295.4

Ref: TM-T23405

Sumatriptan

CAS: 103628-46-2

Formula: C₁₄H₂₁N₃O₂S

Molecular weight: 295.41

Ref: 4Z-S-1115

Sumatriptan

Controlled Product

CAS: 103628-46-2

Applications Sumatriptan is a serotonin 5HT1-receptor agonist.
References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)

Formula: C₁₄H₂₁N₃O₂S

Color and Shape: Neat

Molecular weight: 295.4

Ref: TR-S800095

Sumatriptan - Bio-X ™

CAS: 103628-46-2

Sumatriptan is a serotonin receptor agonist that is used for treating migraines and cluster headaches. This drug binds to 5-HT1B/1D receptors and leads to constriction of cranial blood vessels. It also inhibits the release of pro-inflammatory neuropeptides.

Formula: C₁₄H₂₁N₃O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 295.4 g/mol

Ref: 3D-BS164424

Sumatriptan

CAS: 103628-46-2

5-HT1B/1D serotonin receptor agonist; anti-migraine agent

Formula: C₁₄H₂₁N₃O₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 295.4 g/mol

Ref: 3D-FD146133

Sumatriptan

CAS: 103628-46-2

Purity: 98%

Molecular weight: 295.3999939

Ref: 10-F600616

1-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt

Controlled Product

CAS: 103628-46-2

Formula: C₂₅H₃₃N₅O₄S₂·CH₂O₂

Color and Shape: Neat

Molecular weight: 531.694603

Ref: TR-D492540

Sumatriptan

CAS: 103628-46-2

Formula: C₁₄H₂₁N₃O₂S

Molecular weight: 295.40

Ref: ST-EA-CP-S13000

Sumatriptan

CAS: 103628-46-2

Formula: C₁₄H₂₁N₃O₂S

Color and Shape: Neat

Molecular weight: 295.40

Ref: 04-C17040000