CAS 1037592-40-7

JPH203

Description:

JPH203, with the CAS number 1037592-40-7, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth, differentiation, and metabolism. The compound is often studied for its implications in cancer research, as inhibiting specific kinases can disrupt the signaling pathways that contribute to tumor growth and proliferation. JPH203 may exhibit properties such as solubility in organic solvents, stability under specific conditions, and a defined mechanism of action that targets particular kinases. Its efficacy and safety profile are typically evaluated through preclinical and clinical studies, which assess its pharmacokinetics, bioavailability, and potential side effects. As research continues, JPH203 may contribute to the development of novel therapeutic strategies for diseases associated with dysregulated kinase activity.

Formula: C₂₃H₁₉Cl₂N₃O₄

Synonyms:

• KYT0353
• CS-2494
• KYT-0353;JPH-203;JPH 203
• KYT 0353
• O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine
• KYT-0353;KYT0353;KYT 0353;JPH-203;JPH 203
• L-Tyrosine, O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-
• (S)-2-Amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid
• JPH203
• (KYT-0353
• JPH-203; JPH 203; KYT-0353; KYT 0353; KYT0353.

(S)-2-Amino-3-(4-((5-Amino-2-Phenylbenzo[d]Oxazol-7-Yl)Methoxy)-3,5-Dichlorophenyl)Propanoic Acid

CAS: 1037592-40-7

(S)-2-Amino-3-(4-((5-Amino-2-Phenylbenzo[d]Oxazol-7-Yl)Methoxy)-3,5-Dichlorophenyl)Propanoic Acid

Formula: C₂₃H₁₉Cl₂N₃O₄

Purity: 98%

Molecular weight: 472.32

Ref: 54-OR1023148

JPH203

CAS: 1037592-40-7

JPH203

Formula: C₂₃H₁₉Cl₂N₃O₄

Purity: ≥95%

Molecular weight: 472.32

Ref: 54-BUP04834

JPH203

CAS: 1037592-40-7

JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1).

Formula: C₂₃H₁₉Cl₂N₃O₄

Purity: 97.32% - 99.82%

Color and Shape: Yellow Solid

Molecular weight: 472.32

Ref: TM-TQ0081

O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine

Controlled Product

CAS: 1037592-40-7

Formula: C₂₃H₁₉Cl₂N₃O₄

Color and Shape: Neat

Molecular weight: 472.32

Ref: TR-A627340

JPH203

CAS: 1037592-40-7

JPH203 is a compound that has been shown to inhibit the growth of hypoxic tumor cells. It was found to induce apoptosis in tubule cells through a number of mechanisms, including the inhibition of cyclin D2 protein synthesis and the disruption of cellular signaling pathways. JPH203 is structurally similar to organic anion transporters (OATs), which are drug transporters in the body. This property may help it to cross the blood-brain barrier and reach tumors in the brain. JPH203 has also been shown to inhibit cancer cell proliferation and induce apoptosis in colorectal adenocarcinoma cells, as well as inhibiting tumor growth in animal models.

Formula: C₂₃H₁₉Cl₂N₃O₄

Purity: Min. 95%

Molecular weight: 472.32 g/mol

Ref: 3D-MRB59240

JPH203

CAS: 1037592-40-7

Formula: C₂₃H₁₉Cl₂N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 472.3207

Ref: IN-DA008ZUY