CAS 103898-38-0

Formula: C26H27N5O5

InChI: InChI=1S/C26H27N5O5/c1-16-22(25-28-21(29-36-25)15-30(3)14-18-9-6-5-7-10-18)24(23(17(2)27-16)26(32)35-4)19-11-8-12-20(13-19)31(33)34/h5-13,24,27H,14-15H2,1-4H3

InChI key: HHVCXSOKQHQGFB-UHFFFAOYSA-N

SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C3=NC(=NO3)CN(C)CC4=CC=CC=C4

SM-6586

CAS: 103898-38-0

Formula: C₂₆H₂₇N₅O₅

Molecular weight: 489.5231

Ref: IN-DA01EOHQ

SM 6586

CAS: 103898-38-0

SM 6586 is a dihydropyridine calcium antagonist that inhibits the entry of extracellular calcium into cells. It blocks the influx of calcium ions by blocking voltage-gated L-type calcium channels in smooth muscle cells and neurons. SM 6586 also interacts with other drugs. For example, it has been shown to inhibit the uptake of isradipine by rat brain synaptosomes and prevent isradipine from binding to its target site on the cell membrane. This drug also inhibits the transport of lysine analogs into cells, which may be due to its ability to inhibit cationic amino acid transporter activity. SM 6586 has been shown to have an inhibitory effect on cerebral blood flow in both carotid arteries and ophthalmic veins. The mechanism behind this effect is not yet known.

Formula: C₂₆H₂₇N₅O₅

Purity: Min. 95%

Molecular weight: 489.5 g/mol

Ref: 3D-DEA89838

SM-6586

CAS: 103898-38-0

SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular

Formula: C₂₆H₂₇N₅O₅

Purity: 99.43%

Color and Shape: Yellow Solid

Molecular weight: 489.52

Ref: TM-T16897