CAS 104054-27-5

Atipamezole

Description:

Atipamezole is a selective alpha-2 adrenergic antagonist primarily used in veterinary medicine as a reversal agent for the sedative effects of alpha-2 agonists, such as medetomidine and dexmedetomidine. It is characterized by its ability to rapidly reverse sedation and analgesia in animals, making it valuable in clinical settings. The compound is typically administered via injection and acts by competitively inhibiting the alpha-2 adrenergic receptors, leading to increased release of norepinephrine and subsequent stimulation of the central nervous system. Atipamezole is known for its relatively rapid onset of action and a short duration of effect, which allows for precise control over sedation levels in animals. Additionally, it has a favorable safety profile when used appropriately, although potential side effects may include tachycardia and hypertension. The chemical structure of atipamezole contributes to its pharmacological properties, and it is classified under the broader category of imidazoles. Overall, atipamezole plays a crucial role in veterinary anesthesia and emergency medicine.

Formula: C₁₄H₁₆N₂

InChI: InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)

InChI key: InChIKey=HSWPZIDYAHLZDD-UHFFFAOYSA-N

SMILES: C(C)C1(CC=2C(C1)=CC=CC2)C3=CN=CN3

Synonyms:

• 104054-27-5
• 1H-Imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
• 1H-imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
• 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
• 5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
• Mpv 1248
• Atipamezole

Atipamezole

CAS: 104054-27-5

Formula: C₁₄H₁₆N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 212.2902

Ref: IN-DA008RC7

Atipamezole

CAS: 104054-27-5

Atipamezole

Purity: ≥98%

Molecular weight: 212.29g/mol

Ref: 54-BUP06566

Atipamezole

CAS: 104054-27-5

Formula: C₁₄H₁₆N₂

Purity: ≥ 98.0% (dried basis)

Color and Shape: White, off-white or brown powder

Molecular weight: 212.29

Ref: 7W-GP0527

Atipamezole

CAS: 104054-27-5

Atipamezole

Purity: 98%

Molecular weight: 212.29g/mol

Ref: 54-OR1027526

Atipamezole

CAS: 104054-27-5

Formula: C₁₄H₁₆N₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 212.30

Ref: 3B-A3259

Atipamezole Hydrochloride

CAS: 104054-27-5, 104075-48-1

Formula: C₁₄H₁₆N₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 248.75

Ref: 3B-A2956

Atipamezole

CAS: 104054-27-5

Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.

Formula: C₁₄H₁₆N₂

Purity: 99.88%

Color and Shape: Off-White To Light Yellow Crystal Powder

Molecular weight: 212.29

Ref: TM-T6766

Atipamezole

CAS: 104054-27-5

Applications Atipamezole is a synthetic α2-adrenergic antagonist, usually used to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been shown to be used as possible anti-Parkinsonian drug in humans.
References Pertovaara A., CNS Drug Reviews 11 (3), 273 (2005)

Formula: C₁₄H₁₆N₂

Color and Shape: Neat

Molecular weight: 212.29

Ref: TR-A790095