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CAS 104054-27-5

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Atipamezole

Description:
Atipamezole is a selective alpha-2 adrenergic antagonist primarily used in veterinary medicine as a reversal agent for the sedative effects of alpha-2 agonists, such as medetomidine and dexmedetomidine. It is characterized by its ability to rapidly reverse sedation and analgesia in animals, making it valuable in clinical settings. The compound is typically administered via injection and acts by competitively inhibiting the alpha-2 adrenergic receptors, leading to increased release of norepinephrine and subsequent stimulation of the central nervous system. Atipamezole is known for its relatively rapid onset of action and a short duration of effect, which allows for precise control over sedation levels in animals. Additionally, it has a favorable safety profile when used appropriately, although potential side effects may include tachycardia and hypertension. The chemical structure of atipamezole contributes to its pharmacological properties, and it is classified under the broader category of imidazoles. Overall, atipamezole plays a crucial role in veterinary anesthesia and emergency medicine.
Formula:C14H16N2
InChI:InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)
InChI key:InChIKey=HSWPZIDYAHLZDD-UHFFFAOYSA-N
SMILES:C(C)C1(CC=2C(C1)=CC=CC2)C3=CN=CN3
Synonyms:
  • 104054-27-5
  • 1H-Imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
  • 1H-imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
  • 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
  • 5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
  • Mpv 1248
  • Atipamezole
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