CAS 104104-50-9: Gabazine

Description: Gabazine, also known as SR-95531, is a chemical compound primarily recognized as a selective antagonist of the GABA_A receptor, which plays a crucial role in inhibitory neurotransmission in the central nervous system. Its chemical structure features a bicyclic framework, contributing to its pharmacological properties. Gabazine is often utilized in neuroscience research to study the effects of GABAergic inhibition and to explore the mechanisms underlying various neurological conditions. The compound is known for its ability to block the action of GABA, thereby facilitating the examination of excitatory neurotransmission and synaptic plasticity. Gabazine is typically administered in experimental settings and is not approved for clinical use in humans. Its effects can vary based on concentration and the specific neuronal environment, making it a valuable tool for understanding the complexities of neurotransmitter interactions. Safety and handling precautions are essential when working with Gabazine, as with any chemical compound, to mitigate potential risks associated with its use in laboratory settings.

Formula: C₁₅H₁₇N₃O₃·BrH

InChI: InChI=1S/C15H17N3O3.BrH/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20;/h4-9,16H,2-3,10H2,1H3,(H,19,20);1H

InChI key: InChIKey=GFZHNFOGCMEYTA-UHFFFAOYSA-N

SMILES: Br.O=C(O)CCCN1N=C(C=CC1=N)C=2C=CC(OC)=CC2

Synonyms:

• 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, hydrobromide (1:1)
• 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide
• Gabazine
• SR 95531

SR-95531

CAS: 104104-50-9

• Formula: C₁₅H₁₈BrN₃O₃
• Purity: %
• Color and Shape: Solid
• Molecular weight: 368.2257

2-(3-Carboxypropyl)-3-Amino-6-(4-Methoxyphenyl)Pyridazinium Bromide

CAS: 104104-50-9

• Molecular weight: 368.23g/mol

Gabazine

CAS: 104104-50-9

• Purity: 98.5%
• Molecular weight: 368.23g/mol

Gabazine

CAS: 104104-50-9

Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)

• Formula: C₁₅H₁₈BrN₃O₃
• Purity: 98.51%
• Color and Shape: Solid
• Molecular weight: 368.23

SR 95531 hydrobromide

CAS: 104104-50-9

GABAA receptor antagonist that displaces [3H]-GABA in membranes of rat brain (Ki value 0.15 µM). …

• Formula: C₁₅H₁₇N₃O₃·HBr
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 368.23 g/mol

Gabazine Hydrobromide

CAS: 104104-50-9

• Formula: C₁₅H₁₇N₃O₃·HBr
• Color and Shape: Neat
• Molecular weight: 368.22