CAS 104104-50-9

Gabazine

Description:

Gabazine, also known as SR-95531, is a chemical compound primarily recognized as a selective antagonist of the GABA_A receptor, which plays a crucial role in inhibitory neurotransmission in the central nervous system. Its chemical structure features a bicyclic framework, contributing to its pharmacological properties. Gabazine is often utilized in neuroscience research to study the effects of GABAergic inhibition and to explore the mechanisms underlying various neurological conditions. The compound is known for its ability to block the action of GABA, thereby facilitating the examination of excitatory neurotransmission and synaptic plasticity. Gabazine is typically administered in experimental settings and is not approved for clinical use in humans. Its effects can vary based on concentration and the specific neuronal environment, making it a valuable tool for understanding the complexities of neurotransmitter interactions. Safety and handling precautions are essential when working with Gabazine, as with any chemical compound, to mitigate potential risks associated with its use in laboratory settings.

Formula: C₁₅H₁₇N₃O₃·BrH

InChI: InChI=1S/C15H17N3O3.BrH/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20;/h4-9,16H,2-3,10H2,1H3,(H,19,20);1H

InChI key: InChIKey=GFZHNFOGCMEYTA-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)N1N=C(C=CC1=N)C2=CC=C(OC)C=C2.Br

Synonyms:

• 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, hydrobromide (1:1)
• 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide
• Gabazine
• SR 95531

SR-95531

CAS: 104104-50-9

Formula: C₁₅H₁₈BrN₃O₃

Purity: %

Color and Shape: Solid

Molecular weight: 368.2257

Ref: IN-DA008SG4

Gabazine

CAS: 104104-50-9

Gabazine

Formula: C₁₅H₁₈BrN₃O₃

Purity: ≥98%

Molecular weight: 368.23

Ref: 54-BUP10796

Gabazine

CAS: 104104-50-9

4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid hydrobromide

Formula: C₁₅H₁₈BrN₃O₃

Purity: 95+%

Molecular weight: 368.23

Ref: IN-DG305461

2-(3-Carboxypropyl)-3-Amino-6-(4-Methoxyphenyl)Pyridazinium Bromide

CAS: 104104-50-9

2-(3-Carboxypropyl)-3-Amino-6-(4-Methoxyphenyl)Pyridazinium Bromide

Formula: C₁₅H₁₈BrN₃O₃

Purity: ≥98%

Molecular weight: 368.23

Ref: 54-OR1025320

Gabazine

CAS: 104104-50-9

Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)

Formula: C₁₅H₁₈BrN₃O₃

Purity: 98.51% - 99.24%

Color and Shape: White Solid

Molecular weight: 368.23

Ref: TM-T7622

SR 95531 hydrobromide

CAS: 104104-50-9

GABAA receptor antagonist that displaces [3H]-GABA in membranes of rat brain (Ki value 0.15 µM). Has greater affinity for GABAA than bicuculline (20-fold greater). Inhibits Cl- current induced by GABA, but not pentobarbitone. Low-affinity inhibitor of glycine receptors.

Formula: C₁₅H₁₇N₃O₃·HBr

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 368.23 g/mol

Ref: 3D-BS43265

Gabazine Hydrobromide

Controlled Product

CAS: 104104-50-9

Formula: C₁₅H₁₇N₃O₃·HBr

Color and Shape: Neat

Molecular weight: 368.22

Ref: TR-G122495