CAS 1047645-82-8

GSK2110183B

CAS: 1047645-82-8

Formula: C₁₈H₁₈Cl₃FN₄OS

Purity: %

Color and Shape: Solid

Molecular weight: 463.7841

Ref: IN-DA008TDB

Afuresertib hydrochloride

CAS: 1047645-82-8

Afuresertib hydrochloride

Formula: C₁₈H₁₈Cl₃FN₄OS

Purity: ≥98%

Molecular weight: 463.8

Ref: 54-BUP09723

Afuresertib hydrochloride

CAS: 1047645-82-8

Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)

Formula: C₁₈H₁₈Cl₃FN₄OS

Purity: 99.96%

Color and Shape: Solid

Molecular weight: 463.8

Ref: TM-T7885

Afuresertib HCl

CAS: 1047645-82-8

N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride

Formula: C₁₈H₁₈Cl₃FN₄OS

Purity: 98+%

Molecular weight: 463.78

Ref: IN-DG300977

Afuresertib hydrochloride

CAS: 1047645-82-8

Purity: 98+%

Molecular weight: 462.025

Ref: 10-F857573

Afuresertib hydrochloride

CAS: 1047645-82-8

Afuresertib hydrochloride is a small-molecule inhibitor, which is synthesized as a targeted therapeutic agent. It is specifically designed to inhibit the activity of AKT kinase, a crucial component in the PI3K/AKT/mTOR signaling pathway. This pathway is frequently deregulated in various cancers, contributing to tumor growth, survival, and resistance to conventional therapies.

Formula: C₁₈H₁₈Cl₃FN₄OS

Purity: Min. 95%

Molecular weight: 463.78 g/mol

Ref: 3D-XRB64582