CAS 1051387-90-6

Formula: C22H17FN4O5S

InChI: InChI=1S/C22H17FN4O5S/c23-15-6-4-13(5-7-15)12-24-33(31,32)17-8-9-19-18(11-17)20(21(28)25-19)27-26-16-3-1-2-14(10-16)22(29)30/h1-11,24-25,28H,12H2,(H,29,30)

InChI key: ZSXZSNNAEVDPNL-UHFFFAOYSA-N

SMILES: C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)F)O)C(=O)O

SPI112

CAS: 1051387-90-6

Formula: C₂₂H₁₇FN₄O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.4576

Ref: IN-DA01DU9Z

(Z)-3-(2-(5-(N-(4-Fluorobenzyl)Sulfamoyl)-2-Oxoindolin-3-Ylidene)Hydrazinyl)Benzoic Acid

CAS: 1051387-90-6

(Z)-3-(2-(5-(N-(4-Fluorobenzyl)Sulfamoyl)-2-Oxoindolin-3-Ylidene)Hydrazinyl)Benzoic Acid

Formula: C₂₂H₁₇FN₄O₅S

Purity: 98%

Molecular weight: 468.46

Ref: 54-PC108431

SPI-112

CAS: 1051387-90-6

SPI-112

Formula: C₂₂H₁₇FN₄O₅S

Purity: ≥95%

Molecular weight: 468.46

Ref: 54-BUP14351

SPI-112

CAS: 1051387-90-6

(Z)-3-(2-(5-(N-(4-Fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid

Formula: C₂₂H₁₇FN₄O₅S

Purity: 98%

Molecular weight: 468.46

Ref: IN-DG00831266

SPI-112

CAS: 1051387-90-6

SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity.

Formula: C₂₂H₁₇FN₄O₅S

Purity: 97.51% - >99.99%

Color and Shape: Solid

Molecular weight: 468.46

Ref: TM-T4340

SPI 112

CAS: 1051387-90-6

SPI 112 is a small molecule that inhibits the enzyme phosphatase. SPI 112 has been shown to be effective in mouse tumor models, and it has been found to inhibit growth factor-stimulated cell proliferation. This compound binds to the active site of the phosphatase and dephosphorylates the substrate protein. SPI 112 also inhibits epidermal growth factor (EGF) and interferon alfa-2b induced DNA synthesis in fetal bovine cells. It is not yet known if this drug has any effect on cancer cells grown in culture or radiation-induced apoptosis in human breast cancer cells.

Formula: C₂₂H₁₇FN₄O₅S

Purity: Min. 95%

Molecular weight: 468.46 g/mol

Ref: 3D-BSB38790