CAS 10517-21-2

5-Chloro-1H-indole-2-carboxylic acid

Description:

5-Chloro-1H-indole-2-carboxylic acid is a chemical compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a chlorine atom at the 5-position and a carboxylic acid group at the 2-position contributes to its unique reactivity and properties. This compound typically appears as a solid and is soluble in polar solvents, reflecting its functional groups. It is often utilized in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals due to its potential biological activity. The carboxylic acid group can participate in various chemical reactions, such as esterification and amidation, while the indole moiety is known for its role in biological systems, including neurotransmitter function. Additionally, the chlorine substituent can influence the compound's lipophilicity and biological interactions. Overall, 5-Chloro-1H-indole-2-carboxylic acid is a versatile compound with applications in research and development within the fields of chemistry and pharmacology.

Formula: C₉H₆ClNO₂

InChI: InChI=1S/C9H6ClNO2/c10-6-1-2-7-5(3-6)4-8(11-7)9(12)13/h1-4,11H,(H,12,13)

InChI key: InChIKey=FUQOTYRCMBZFOL-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1NC=2C(C1)=CC(Cl)=CC2

Synonyms:

• 1H-Indole-2-carboxylic acid, 5-chloro-
• 2-Carboxy-5-chloroindole
• 5-Chloro-1H-indole-2-carboxylic acid
• 5-chloro-1H-indole-2-carboxylate
• Indole-2-carboxylic acid, 5-chloro-
• NSC 75651
• 5-Chloroindole-2-carboxylic acid

5-Chloroindole-2-carboxylic Acid

CAS: 10517-21-2

Formula: C₉H₆ClNO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 195.60

Ref: 3B-C1868

5-Chloroindole-2-carboxylic acid

CAS: 10517-21-2

Formula: C₉H₆ClNO₂

Molecular weight: 195.60

Ref: 7W-GK1985

5-Chloroindole-2-carboxylic acid

CAS: 10517-21-2

5-Chloroindole-2-carboxylic acid

Formula: C₉H₆ClNO₂

Purity: >98%

Color and Shape: Solid

Molecular weight: 195.60244

Ref: 54-OR10933

5-Chloroindole-2-carboxylic acid

CAS: 10517-21-2

Formula: C₉H₆ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.6024

Ref: IN-DA0038ZV

5-Chloroindole-2-carboxylic acid

CAS: 10517-21-2

Formula: C₉H₆ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.6

Ref: 10-F077200

5-Chloro-1H-indole-2-carboxylic acid

CAS: 10517-21-2

5-Chloro-1H-indole-2-carboxylic acid

Formula: C₉H₆ClNO₂

Purity: 97%

Molecular weight: 195.6

Ref: IN-DG8391

5-Chloroindole-2-carboxylic Acid

Controlled Product

CAS: 10517-21-2

Applications 5-Chloroindole-2-carboxylic Acid is used in the synthesis of 4-(3-aminomethylphenyl)piperidine-1-carboxamides as potent, selective, and orally bioavailable inhibitors of βII tryptase. It is also a reagent used to prepare indole amides with possible antihistaminic activities.
References Levell, J., et al.: Bioorg. Med. Chem., 13, 2859 (2005); Battaglia, S., et al.: Eur. J. Med. Chem., 34, 93 (1999)

Formula: C₉H₆ClNO₂

Color and Shape: Neat

Molecular weight: 195.6

Ref: TR-C377710