![Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F382836-5-o-44-dimethoxytrityl-5-methyl-n4-benzoyl-2-deoxycytidine-3-2-cyanoethyl-n-n-diisopropyl-phosphoramidite.webp&w=3840&q=75)
CAS 105931-57-5
:Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Description:
Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This substance features a cytidine base, which is a nucleoside composed of a pyrimidine ring and a ribose sugar, modified with a benzoyl group and a phosphoramidite moiety. The presence of the bis(4-methoxyphenyl)phenylmethyl group enhances its stability and solubility, making it suitable for various biochemical applications. The cyanoethyl phosphoramidite functionality allows for efficient coupling reactions during oligonucleotide synthesis, facilitating the formation of phosphodiester bonds. This compound is characterized by its ability to participate in selective reactions, contributing to the development of synthetic methodologies in molecular biology and genetic engineering. Its CAS number, 105931-57-5, serves as a unique identifier for regulatory and research purposes.
Formula:C47H54N5O9P
InChI:InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
InChI key:InChIKey=AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Synonyms:- 4: PN: US20030212017 PAGE: 17 claimed DNA
- 5'-O-(4,4'-Dimethoxytrityl)-5-Methyl-N4-Benzoyl-2'-Deoxycytidine-3'-(2-Cyanoethyl-N,N-Diisopropyl)Phosphoramidite
- 5: PN: US20030211606 PAGE: 17 claimed DNA
- 6: PN: US20040014048 PAGE: 18 claimed DNA
- 6: PN: US20040014049 PAGE: 18 claimed DNA
- 7: PN: US20030198965 PAGE: 17 claimed DNA
- 7: PN: US20040014047 PAGE: 18 claimed DNA
- 80: PN: US20040005707 PAGE: 18 claimed DNA
- 8: PN: US20040005565 PAGE: 17-22 claimed DNA
- 8: PN: US20040005569 PAGE: 20 claimed DNA
- 8: PN: US20040005570 PAGE: 18 claimed DNA
- 8: PN: US20040006029 PAGE: 20 claimed DNA
- 8: PN: US20040006030 PAGE: 20 claimed DNA
- 8: PN: US20040014050 PAGE: 18 claimed DNA
- 8: PN: US20040014051 PAGE: 20 claimed DNA
- 8: PN: US20040014699 PAGE: 18 claimed DNA
- 8: PN: WO03106645 PAGE: 64 claimed DNA
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- N4-Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
- DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite
- 5'-O-DMT-N4-Benzoyl-2'-Deoxy-5-Methylcytidine-CE Phosphoramidite
- 5-Me-DMT-dC(Bz)-CE
- N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine-3'-cyanoethyl Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE Phosphoramidite
- 8: PN: US20040014050 PAGE
- 5-methyldeoxycytidine-ce*phosphoramidite for cycl
- 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite
- US20040006030 PAGE: 20 claimed DNA
- 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5-Me-dCBzPhosphoramidite
- deoxy N-Bz 5-Me Cytidine Amidite
- 2'-deoxycytidine-3'-cyanoethyl
- Phosphoramidite
- N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]-5-methyl-2-oxo-pyrimidin-4-yl]benzamide
- N-blocked-5'-O-DMT CED methyldeoxycytidine phosphoramidite
- 5-Me-DMT-dC(Bz)-CE Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
- 5'-O-(4,4'-DiMethoxytrityl)-N4-benzoyl-2'-deoxy-5-Methylcytidine-3'- O-(O-2-cyanoethyl-N,N-diisopropylaMino) phosphoraMidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-cytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- DMT-5Me-dC(Bz)-CE Phosphoramidite
- N4-benzoyl-5-methyl-5'-O-(4, 4'-dimethoxytrityl)-
- Bz-5-Me-dC phosphoramidite
- 5-Me Bz dC Beta-Cyanoethyl Phosphoramidite (500 mg) (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
- 5-Me-dC CE Phosphoramidite
- Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- N -Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl-N,N-diisopropylphosphoramidite(DMT-5-MedC(bz)phosphoramidite)
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
5-Me Bz dC β-Cyanoethyl Phosphoramidite (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C47H54N5O8PColor and Shape:White PowderMolecular weight:847.3715'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
CAS:Formula:C47H54N5O8PPurity:98%Color and Shape:SolidMolecular weight:847.9341DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:<p>DMT-5Me-dC(Bz)-CE Phosphoramidite</p>Purity:99%Molecular weight:847.93g/molDMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:<p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>Formula:C47H54N5O8PColor and Shape:SolidMolecular weight:847.93DMT-5-Me-dC(Bz) Phosphoramidite
CAS:Formula:C47H54N5O8PPurity:>95.0%(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:847.95N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.</p>Formula:C47H54N5O8PPurity:Min. 95%Color and Shape:White PowderMolecular weight:847.93 g/mol
