CAS 106133-20-4: Tamsulosin

Description: Tamsulosin is a selective alpha-1 adrenergic antagonist primarily used in the treatment of benign prostatic hyperplasia (BPH) to alleviate urinary symptoms. It works by relaxing the smooth muscles in the prostate and bladder neck, facilitating easier urination. The chemical formula of Tamsulosin is C20H28N2O5S, and it features a sulfonamide group, which contributes to its pharmacological activity. Tamsulosin is characterized by its high oral bioavailability and relatively long half-life, allowing for once-daily dosing. It is typically administered in the form of capsules. The substance is known for its favorable side effect profile compared to non-selective alpha blockers, with a lower incidence of cardiovascular effects. However, it may still cause side effects such as dizziness, headache, and abnormal ejaculation. Tamsulosin is classified as a prescription medication and should be used under medical supervision, particularly in patients with a history of orthostatic hypotension or those taking other antihypertensive medications.

Formula: C₂₀H₂₈N₂O₅S

InChI: InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1

InChI key: InChIKey=DRHKJLXJIQTDTD-OAHLLOKOSA-N

SMILES: O=S(=O)(N)C1=CC(=CC=C1OC)CC(NCCOC=2C=CC=CC2OCC)C

Synonyms:

• 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide
• Tamsulosin
• Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-
• Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, (R)-
• Amsulosin

Tamsulosin Hydrochloride

CAS: 106133-20-4106463-17-6

• Formula: C₂₀H₂₈N₂O₅S·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 444.97

Tamsulosin

CAS: 106133-20-4

• Formula: C₂₀H₂₈N₂O₅S
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 408.5117

Tamsulosin

CAS: 106133-20-4

• Formula: C₂₀H₂₈N₂O₅S
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder or crystals
• Molecular weight: 408.51

Tamsulosin

CAS: 106133-20-4

Tamsulosin: an alpha1A blocker for easing urination in BPH by relaxing prostate and bladder muscles.

• Formula: C₂₀H₂₈N₂O₅S
• Purity: 99.94%
• Color and Shape: White Crystals
• Molecular weight: 408.51

(R)-Tamsulosin

CAS: 106133-20-4

• Formula: C₂₀H₂₈N₂O₅S
• Molecular weight: 408.52

5-(2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide

CAS: 106133-20-4

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• Formula: C₂₀H₂₈N₂O₅S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 408.51 g/mol