CAS 106463-17-6

Tamsulosin Hydrochloride

Description:

Tamsulosin Hydrochloride is a selective alpha-1 adrenergic antagonist primarily used in the treatment of benign prostatic hyperplasia (BPH) to alleviate urinary symptoms. It works by relaxing the smooth muscles in the prostate and bladder neck, facilitating easier urination. The substance is typically administered orally and is known for its relatively high bioavailability and moderate protein binding. Tamsulosin is characterized by its chemical formula, which includes a sulfonamide group, contributing to its pharmacological activity. The compound exhibits a half-life that allows for once-daily dosing, making it convenient for patients. Common side effects may include dizziness, headache, and orthostatic hypotension, particularly upon initiation of therapy. Tamsulosin Hydrochloride is classified as a prescription medication and should be used under medical supervision, especially in patients with a history of cardiovascular issues. Its safety profile and efficacy have been established through various clinical trials, making it a widely prescribed option for managing urinary symptoms associated with prostate enlargement.

Formula:C₂₀H₂₈N₂O₅S·ClH

InChI:InChI=1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1

InChI key:InChIKey=ZZIZZTHXZRDOFM-XFULWGLBSA-N

SMILES:S(N)(=O)(=O)C1=C(OC)C=CC(C[C@H](NCCOC2=C(OCC)C=CC=C2)C)=C1.Cl

Synonyms:

(-)-(R)-5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide hydrochloride
(-)-Ly 253352
(-)-Ym 12617
(R)-(-)-Ym 12617
5-(2-{[2-(2-Ethoxyphenoxy)Ethyl]Amino}Propyl)-2-Methoxybenzenesulfonamide Hydrochloride
5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, hydrochloride (1:1)
Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride
Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride, (R)-
Dynapress
Flomax
Harnal
Ly 253351
Omnic
Tamsulosin HCL
Tamuzosin hydrochloride
Urimax
Uripro
Ym 12617-1
Ym 617
Yutanal
idehydrochloride
r-(-)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonam
(r)-onohydrochlorid
PRADIF
5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-,monohydrochloride,(r)-benzenesulfonamid
TAMSULOSIN, HYDROCHLORIDE 99.5%
(-)-ym12617
TAMSULOSIN HYDROCHLORIDE
TAMSOLUSIN HYDROCHLORIDE
(-)-ly253352
5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-benzenesulfonamidm
See more synonyms