CAS 1063-77-0

Nomilin

Description:

Nomilin, with the CAS number 1063-77-0, is a naturally occurring compound classified as a limonoid, primarily found in citrus fruits, particularly in the seeds and peels. It is known for its bitter taste and is part of a larger group of compounds that exhibit various biological activities. Nomilin has garnered interest for its potential health benefits, including anti-inflammatory, antioxidant, and anticancer properties. Its structure features a complex arrangement of carbon rings and functional groups, contributing to its unique chemical behavior. In addition to its biological significance, Nomilin is also studied for its potential applications in food preservation and as a natural pesticide due to its insecticidal properties. However, further research is needed to fully understand its mechanisms of action and potential therapeutic uses. Overall, Nomilin represents a fascinating area of study within the field of natural products and their applications in health and agriculture.

Formula: C₂₈H₃₄O₉

InChI: InChI=1/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16?,17?,19-,21+,22-,25+,26-,27+,28-/m1/s1

InChI key: InChIKey=KPDOJFFZKAUIOE-WNGDLQANSA-N

SMILES: C[C@]12[C@]34[C@](C)([C@@H](OC(=O)[C@]3(O4)[H])C=5C=COC5)CC[C@@]1([C@]6(C)[C@@](CC2=O)(C(C)(C)OC(=O)C[C@@H]6OC(C)=O)[H])[H]

Synonyms:

• (1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-11-(Acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
• (5R,5aR,7aS,8R,10aS,11aR,11bR)-8-furan-3-yl-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate
• (5S,5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate
• 1-(Acetyloxy)-1,2-dihydroobacunoic acid eta-lactone
• 8-(Furan-3-Yl)-1,1,5A,7A,11B-Pentamethyl-3,10,12-Trioxohexadecahydrooxireno[4,4A]Isochromeno[6,5-G][2]Benzoxepin-5-Yl Acetate
• Ai3-37935
• Nsc 297134
• Obacunoic acid, 1-(acetyloxy)-1,2-dihydro-, eta-lactone
• Obacunoic acid, 1-(acetyloxy)-1,2-dihydro-, ε-lactone
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furyl)decahydro-11-hydroxy-4b,7,7,11a,13a-pentamethyl-, acetate
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 11-(acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 11-(acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyl-, [1S-(1α,3aα,4aS*,4bβ,6aα,11α,11aβ,11bα,13aα)]-
• Nomilin
• fromcitrusseeds
• NOMILIN(P)(CALL)
• NOMILIN(RG)
• Nomilin (~85%)
• Nomilin, 98.5%, from Rutaceae
• 1-(Acetyloxy)-1,2-dihydroobacunoic acid epislon-lactone
• Nomilin USP/EP/BP
• NoMilin, froM Rutaceae
• 1-(Acetyloxy)-1,2-dihydroobacunoic acid ε-lactone
• (1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-1-(Furan-3-yl)-4b,7,7,11a,13a-pentamethyl-3,5,9-trioxohexadecahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromen-11-yl acetate

Nomilin

CAS: 1063-77-0

Formula: C₂₈H₃₄O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 514.5642

Ref: IN-DA007CZN

Nomilin

CAS: 1063-77-0

Nomilin

Formula: C₂₈H₃₄O₉

Purity: 98%

Molecular weight: 514.56

Ref: 54-OR1026644

Nomilin

CAS: 1063-77-0

Nomilin

Formula: C₂₈H₃₄O₉

Purity: ≥95%

Molecular weight: 514.571

Ref: 54-BUP10664

Nomilin

CAS: 1063-77-0

Formula: C₂₈H₃₄O₉

Molecular weight: 514.56

Ref: 7W-GP5326

Nomilin

CAS: 1063-77-0

Nomilin has immunomodulatory, antioxidant, anti-human immunodeficiency virus(HIV), cancer chemopreventive, antiangiogenic, anti-obesity and anti-hyperglycemic effects. Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. It inhibits osteoclastogenesis in vitro by suppression of NFATc1 and MAPK signaling pathways, indicates that nomilin-containing herbal preparations have potential utility for the prevention of bone metabolic diseases.

Formula: C₂₈H₃₄O₉

Purity: 95%~99%

Molecular weight: 514.571

Ref: BP-BP1003

Nomilin

CAS: 1063-77-0

Nomilin is naturally occurring triterpenoids, have immunomodulatory activity.

Formula: C₂₈H₃₄O₉

Purity: 98.04% - 99.84%

Color and Shape: Slightly Off-White Solid

Molecular weight: 514.56

Ref: TM-T3672

Nomilin

CAS: 1063-77-0

Lactone

Formula: C₂₈H₃₄O₉

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 514.57

Ref: 5G-80507

Nomilin (~85%)

Controlled Product

CAS: 1063-77-0

Applications Nomilin is a inducer of phase II detoxifying enzymes.
References Kimira, Y. et al.: Phytomed., 22, 1120, (2015); Xiang, Y. et al.: J. Food Sci., 79, C1956 (2013);

Formula: C₂₈H₃₄O₉

Purity: ~85%

Color and Shape: Neat

Molecular weight: 514.56

Ref: TR-N635953

Nomilin

CAS: 1063-77-0

Nomilin is a limonoid, which is a type of triterpenoid compound. This chemical is derived from the seeds and peels of citrus fruits, especially those belonging to the Rutaceae family, such as oranges and grapefruits. In plants, limonoids serve various roles, including defense against pathogens.

Formula: C₂₈H₃₄O₉

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 514.56 g/mol

Ref: 3D-FN59572

Nomilin

CAS: 1063-77-0

(1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-1-(Furan-3-yl)-4b,7,7,11a,13a-pentamethyl-3,5,9-trioxohexadecahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromen-11-yl acetate

Formula: C₂₈H₃₄O₉

Purity: 98%

Molecular weight: 514.56

Ref: IN-DG145382

Nomilin

CAS: 1063-77-0

Purity: 98%

Molecular weight: 514.571

Ref: 10-F979123