CAS: 106400-81-1 - Lometrexol

Formula: C₂₁H₂₅N₅O₆

InChI: InChI=1/C21H25N5O6/c22-21-25-17-14(19(30)26-21)9-12(10-23-17)2-1-11-3-5-13(6-4-11)18(29)24-15(20(31)32)7-8-16(27)28/h3-6,12,15H,1-2,7-10H2,(H,24,29)(H,27,28)(H,31,32)(H4,22,23,25,26,30)/t12-,15+/m1/s1

Synonyms:

• Lometrexolum
• Lometrexolum [INN-Latin]
• Unii-6P3Avy8A7Q
• L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-
• L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-
• N-(4-{2-[(6R)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid

Lometrexol hydrate

CAS: 106400-81-1

• Formula: C₂₁H₂₅N₅O₆
• Molecular weight: 443.45

Lometrexol Hydrate

CAS: 106400-81-1

Applications It is an antifolate which inhibits glycinamide ribonucleotide formyltransferase (GARFT), an enzyme essential for …

• Formula: C₂₁H₂₅N₅O₆·xH₂O
• Color and Shape: Neat
• Molecular weight: 443.45 + x(18.02)

Lometrexol Hydrate

CAS: 106400-81-1

Lometrexol is an anti-cancer drug that belongs to the class of polymerase chain inhibitors. It …

• Formula: C₂₁H₂₅N₅O₆·xH₂O
• Purity: Min. 95%
• Molecular weight: 443.45 g/mol

Lometrexol

CAS: 106400-81-1

Lometrexol (LY 264618) is an antifolate that inhibits GARFT, blocks purine synthesis, induces apoptosis, and …

• Formula: C₂₁H₂₅N₅O₆
• Purity: 98.57% - 99.35%
• Color and Shape: Solid
• Molecular weight: 443.45