CAS 1069046-00-9

Formula: C35H38N2O6

InChI: InChI=1S/C31H27NO3.C4H11NO3/c33-31(34)20-13-24-12-19-30-29(21-24)25(14-11-23-7-3-1-4-8-23)22-32(30)26-15-17-28(18-16-26)35-27-9-5-2-6-10-27;5-4(1-6,2-7)3-8/h1-10,12,15-19,21-22H,11,13-14,20H2,(H,33,34);6-8H,1-3,5H2

InChI key: MBPXGBINIINSEU-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)CCC2=CN(C3=C2C=C(C=C3)CCC(=O)O)C4=CC=C(C=C4)OC5=CC=CC=C5.C(C(CO)(CO)N)O

ASB 14780

CAS: 1069046-00-9

ASB 14780

Formula: C₃₅H₃₈N₂O₆

Purity: ≥98%

Molecular weight: 582.7

Ref: 54-OR1153567

ASB 14780New

CAS: 1069046-00-9

ASB 14780New is a novel small molecule that has been shown to reduce the inflammatory response by inhibiting the production of inflammatory cells and decreasing the accumulation of collagen. ASB 14780New targets senescent cells, which are cells that have stopped dividing and accumulate in various tissues and organs. The drug also affects markers present in cytosolic extracts from muscle cells, such as growth factor-β1 (GF-β1) and cox-1. It has been shown to inhibit cholesterol absorption and promote its excretion through the bile. ASB 14780New also reduces inflammation caused by carbon tetrachloride or an experimental diet rich in cholesterol. ASB 14780New is being studied for its potential therapeutic effects in Alzheimer's disease, where it may be able to reduce inflammation by targeting senescent cells.

Formula: C₃₁H₂₇NO₃·C₄H₁₁NO₃

Purity: Min. 95%

Molecular weight: 582.7 g/mol

Ref: 3D-USB04600

ASB 14780

CAS: 1069046-00-9

ASB 14780 is a 4-phenoxy derivative that exhibits highly selective inhibition of cytosolic phospholipase A2α (cPLA2α), with an IC₅₀ value as low as 20 nM.

Formula: C₃₅H₃₈N₂O₆

Purity: 99.71%

Color and Shape: White Solid

Molecular weight: 582.70

Ref: TM-T37842