CAS 1070663-78-3

Dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine

Description:

Dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine, identified by CAS number 1070663-78-3, is a phosphine compound characterized by its complex structure featuring a phosphine moiety attached to a biphenyl framework. This compound typically exhibits properties associated with phosphines, such as being a good ligand in coordination chemistry, particularly in catalysis and organic synthesis. The presence of methoxy groups enhances its solubility in organic solvents and may influence its reactivity and stability. The bulky cyclohexyl groups contribute to steric hindrance, which can affect its coordination properties and the overall reactivity of the compound. Additionally, the presence of multiple alkyl substituents on the biphenyl structure can enhance its electronic properties, making it suitable for various applications in organic synthesis and catalysis. Overall, this compound is of interest in the field of organometallic chemistry and may serve as a valuable ligand in transition metal complexes.

Formula: C₃₅H₅₃O₂P

InChI: InChI=1S/C35H53O2P/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28/h19-25,27-28H,9-18H2,1-8H3

InChI key: InChIKey=WDVGNXKCFBOKDF-UHFFFAOYSA-N

SMILES: P(C1=C(C(OC)=CC=C1OC)C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)(C3CCCCC3)C4CCCCC4

Synonyms:

• 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl
• 2-Dicyclohexylphosphino-3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl
• 3,6-Dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl-2-yl]dicyclohexylphosphine
• BrettPhos
• Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-2-biphenylyl)phosphine
• Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine
• Dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine
• Phosphine, dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]-

Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine

CAS: 1070663-78-3

Formula: C₃₅H₅₃O₂P

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 536.78

Ref: 3B-D5664

2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% BrettPhos

CAS: 1070663-78-3

2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% BrettPhos

Formula: C₃₅H₅₃O₂P

Purity: min. 98%

Color and Shape: white xtl.

Molecular weight: 536.77

Ref: 08-15-1152

2-(Dicyclohexylphosphino)3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl

CAS: 1070663-78-3

Formula: C₃₅H₅₃O₂P

Purity: 98%

Color and Shape: Solid

Molecular weight: 536.7679

Ref: IN-DA0032VF

BrettPhos

CAS: 1070663-78-3

BrettPhos

Formula: C₃₅H₅₃O₂P

Purity: 93%

Color and Shape: Solid

Molecular weight: 536.76788

Ref: 54-OR938150

2-(Dicyclohexylphosphino)-3,6-dimethoxy-2′-4′-6′-tri-i-propyl-1,1′-biphenyl

CAS: 1070663-78-3

Formula: C₃₅H₅₃O₂P

Purity: 97%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 536.781

Ref: 10-F545966

BrettPhos

CAS: 1070663-78-3

Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine

Formula: C₃₅H₅₃O₂P

Purity: 97%

Molecular weight: 536.77

Ref: IN-DG212547

BrettPhos

Controlled Product

CAS: 1070663-78-3

Applications BrettPhos is used in cross C-N coupling reactions, acting as a biarylmonophosphine catalyst.
References Fors, B. et al.: J. Am. Chem. Soc., 130, 13552 (2008);

Formula: C₃₅H₅₃O₂P

Color and Shape: Neat

Molecular weight: 536.77

Ref: TR-B677380

2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl

CAS: 1070663-78-3

2-(Dicyclohexylphosphino)3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl is a palladium complex that is used as an inhibitor drug for the treatment of cancer. It is able to inhibit the growth of skin cancer cells by blocking the action of certain growth factors. 2-(Dicyclohexylphosphino)3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl binds to nitrogen atoms and amines in cancer cells and halides in inflammatory diseases. This binding inhibits the formation of reactive oxygen species and causes cell death. The compound also has anti-inflammatory properties.

Formula: C₃₅H₅₃O₂P

Purity: Min. 95%

Molecular weight: 536.77 g/mol

Ref: 3D-FD44708