CAS 108050-54-0
:tilmicosin
Description:
Tilmicosin is a semi-synthetic macrolide antibiotic primarily used in veterinary medicine, particularly for the treatment of respiratory infections in livestock, such as cattle and swine. It is derived from the fermentation of the bacterium *Streptomyces fradiae*. Tilmicosin exhibits a broad spectrum of activity against various Gram-positive bacteria and some Gram-negative bacteria, making it effective in combating infections caused by pathogens like *Mycoplasma* and *Pasteurella*. The compound works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. Tilmicosin is typically administered via injection or in feed formulations, and it is known for its long half-life, allowing for less frequent dosing. However, it is important to note that tilmicosin can be toxic to certain animal species, particularly horses and humans, leading to potential safety concerns. As with all antibiotics, the use of tilmicosin should be managed carefully to prevent the development of antibiotic resistance.
Formula:C46H80N2O13
InChI:InChI=1/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1
InChI key:InChIKey=JTSDBFGMPLKDCD-XVFHVFLVSA-N
SMILES:O([C@H]1[C@@H](CCN2C[C@@H](C)C[C@@H](C)C2)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]3[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)[C@H](O)[C@@H](C)O4
Synonyms:- 20-Deoxo-20-(3,5-Dimethyl-1-Piperidinyl)Desmycosin
- 4<sup>A</sup>-O-De(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
- 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
- Antibiotic EL 870
- El 870
- Ly 177370
- Micotil
- Micotil 300
- Oxacyclohexadecane, tylosin deriv.
- Provitil
- Pulmotil
- Tilmicosin, Vetranal
- Tilmicosin base
- Tylmicosine
- Tylosin, 4<sup>A</sup>-O-de(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
- Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl-
- [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-11-{2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxooxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
- cis-Tilmicosin
- Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
- (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione
- 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870
- 20%Tilmicosin
- Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
- TILMICOSIN
- 4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic]
- Tilmicosine
- Tilmicosin (250 mg)
- See more synonyms
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Found 13 products.
Tilmicosin
CAS:Antibiotics nesoiFormula:C46H80N2O13Color and Shape:White Off-White PowderMolecular weight:868.56604Tilmicosin
CAS:Tilmicosin (EL-870), a macrolide antibiotic, treats bovine and ovine respiratory diseases in animals.Formula:C46H80N2O13Purity:97.84% - 99.5%Color and Shape:SolidMolecular weight:869.13Tilmicosin, 10mM (in DMSO)
CAS:Tilmicosin, 10mM (in DMSO)Formula:C46H80N2O13Purity:≥95%, 10 mM in DMSOMolecular weight:869.13Tilmicosin
CAS:Formula:C46H80N2O13Purity:≥ 85.0% (anhydrous basis)Color and Shape:White to off-white powderMolecular weight:869.13Tilmicosin 100 µg/mL in Acetonitrile
CAS:Formula:C46H80N2O13Color and Shape:Single SolutionMolecular weight:869.13Tilmicosin, 85%
CAS:Applications Macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989), Ose, E.E., et al.: Vet. Rec., 123, 367 (1988), Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993),Formula:C46H80N2O13Purity:85%Color and Shape:NeatMolecular weight:869.13Tilmicosin-d3
CAS:Controlled ProductApplications Tilmicosin-d3 is the labeled analogue of Tilmicosin (T440500), a macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989); Ose, E.E., et al.: Vet. Rec., 123, 367 (1988); Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993)Formula:C46H77D3N2O13Color and Shape:NeatMolecular weight:872.15Tilmicosin
CAS:Tilmicosin is a macrolide antibiotic with action on bacterial protein synthesis inhibition and is used for treating respiratory infections in cattle and sheep.Formula:C46H80N2O13Purity:Min. 85 Area-%Color and Shape:White PowderMolecular weight:869.13 g/molTilmicosin - Bio-X ™
CAS:Tilmicosin is a macrolide antibiotic that is used in veterinary medicine. It is used to treat bovine respiratory disease and inhibits bacterial growth by binding to the 50S ribosomal subunit of the bacteria resulting in reduced protein synthesis.
Formula:C46H80N2O13Purity:Min. 95%Color and Shape:PowderMolecular weight:869.13 g/mol
