CAS 108321-42-2

Geneticin sulfate

Description:

Geneticin sulfate, also known as G418, is an aminoglycoside antibiotic that is primarily used in molecular biology for the selection of genetically modified cells. It is effective against a wide range of bacteria and is particularly known for its ability to inhibit protein synthesis by binding to the 30S ribosomal subunit. This compound is often utilized in cell culture to select for cells that have been transfected with plasmids containing a genetic marker for resistance to Geneticin. The sulfate form enhances its solubility in aqueous solutions, making it suitable for laboratory applications. Geneticin is typically used at concentrations that vary depending on the cell type and experimental conditions. It is important to handle Geneticin sulfate with care, as it can be toxic to non-resistant cells. Additionally, due to its antibiotic properties, it is crucial to consider potential effects on microbial flora in experimental setups. Overall, Geneticin sulfate is a valuable tool in genetic engineering and cell biology research.

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

InChI: InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1

InChI key: InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Synonyms:

• (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
• ANTIBIOTIC G-418 Sulfate
• G-418 Sulfate
• G-418 Sulphate
• G418 Disulfate Cell Culture Tested
• G418 Disulfate Plant Cell Culture Tested
• G418 Solution
• G418 Sulfate
• Geneticin sulfate
• Sulfuric Acid
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)

G418 disulfate, Cell Culture Reagent

CAS: 108321-42-2

G418 disulfate, cell culture reagent, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1. Learn more at Thermo Fisher Scientific.

Formula: C₂₀H₄₄N₄O₁₈S₂

Color and Shape: White, Powder

Molecular weight: 692.70

Ref: 02-J62671

G418 disulfate, 50mg/ml solution

CAS: 108321-42-2

G418 disulfate, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1 suitable for cell culture. Learn more at Thermo Fisher Scientific.

Formula: C₂₀H₄₄N₄O₁₈S₂

Color and Shape: Liquid, Clear colorless

Molecular weight: 692.70

Ref: 02-J63871

G 418 Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₄N₄O₁₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 692.7094

Ref: IN-DA00HB58

G-418 Disulphate

CAS: 108321-42-2

G-418 Disulphate

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purity: 99.9%

Color and Shape: solid

Molecular weight: 692.71g/mol

Ref: 54-BIG0175

G-418 Sulphate solution 50mg/ml

CAS: 108321-42-2

G-418 Sulphate solution 50mg/ml

Color and Shape: Solution

Molecular weight: 594.63088g/mol

Ref: 54-BIG0176

G418 disulphate salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purity: ≥ 720μg/mg

Color and Shape: White to almost white powder

Molecular weight: 692.71

Ref: 7W-GA2946

G418 disulphate salt, 10% solution in water

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Color and Shape: Clear, colourless liquid

Molecular weight: 692.71

Ref: 7W-GP6404

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate

Purity: ≥98%

Molecular weight: 692.71g/mol

Ref: 54-BUP18758

G-418.Sulfate Solid

CAS: 108321-42-2

M01801 - G-418.Sulfate Solid

Formula: C₂₀H₄₄N₄O₁₈S₂

Purity: >90.0%(HPLC)(N)

Color and Shape: Solid

Molecular weight: 692.7

Ref: 10-M01801

Geneticin Disulfate

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Molecular weight: 496.56 2*98.07

Ref: 4Z-G-215001

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Purity: 98% - 99.9%

Color and Shape: White To Off-White Powder

Molecular weight: 692.71

Ref: TM-T6512

Geneticin sulfate

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 692.71 g/mol

Ref: 3D-AG11347

G418 Disulfate

CAS: 108321-42-2, 49863-47-0

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purity: >90.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 692.70

Ref: 3B-G0349

G-418 Sulphate (Geneticin) for tissue culture

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Color and Shape: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Molecular weight: 692.70

Ref: SR-87858

G-418 Sulphate (Geneticin) extrapure

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Color and Shape: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Molecular weight: 692.70

Ref: SR-58327

G-418.Sulfate, Sterile-Filtered Solution

CAS: 108321-42-2

M01802 - G-418.Sulfate, Sterile-Filtered Solution

Formula: C₂₀H₄₄N₄O₁₈S₂

Purity: >90.0%(HPLC)(N)

Color and Shape: Liquid

Molecular weight: 692.7

Ref: 10-M01802

Geneticin Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Color and Shape: White To Off-White

Molecular weight: 692.71

Ref: TR-G360580

Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Formula: C₂₀H₄₄N₄O₁₈S₂

Purity: Min. 97.0 Area-%

Molecular weight: 692.71 g/mol

Ref: 3D-G-2400

Geneticin Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀(H₂SO₄)

Molecular weight: 496.56 : 2(98.07)

Ref: ST-EA-CP-G33036