CAS 108321-42-2: Geneticin sulfate

Description: Geneticin sulfate, also known as G418, is an aminoglycoside antibiotic that is primarily used in molecular biology for the selection of genetically modified cells. It is effective against a wide range of bacteria and is particularly known for its ability to inhibit protein synthesis by binding to the 30S ribosomal subunit. This compound is often utilized in cell culture to select for cells that have been transfected with plasmids containing a genetic marker for resistance to Geneticin. The sulfate form enhances its solubility in aqueous solutions, making it suitable for laboratory applications. Geneticin is typically used at concentrations that vary depending on the cell type and experimental conditions. It is important to handle Geneticin sulfate with care, as it can be toxic to non-resistant cells. Additionally, due to its antibiotic properties, it is crucial to consider potential effects on microbial flora in experimental setups. Overall, Geneticin sulfate is a valuable tool in genetic engineering and cell biology research.

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

InChI: InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1

InChI key: InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N

SMILES: O=S(=O)(O)O.OC(C)C1OC(OC2C(O)C(OC3OCC(O)(C)C(NC)C3O)C(N)CC2N)C(N)C(O)C1O

Synonyms:

• (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
• ANTIBIOTIC G-418 Sulfate
• G-418 Sulfate
• G-418 Sulphate
• G418 Disulfate Cell Culture Tested
• G418 Disulfate Plant Cell Culture Tested
• G418 Solution
• G418 Sulfate
• Geneticin sulfate
• Sulfuric Acid
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)

G418 disulfate, Cell Culture Reagent

CAS: 108321-42-2

G418 disulfate is an aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths. It …

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Color and Shape: White, Powder
• Molecular weight: 692.70

G418 disulfate, 50mg/ml solution

CAS: 108321-42-2

G418 disulfate is used for selection and maintenance of prokaryotic and eukaryotic cells transfected with …

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Color and Shape: Liquid, Clear colorless
• Molecular weight: 692.70

G-418.Sulfate Solid

CAS: 108321-42-2

M01801 - G-418.Sulfate Solid

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Purity: >90.0%(HPLC)(N)
• Color and Shape: Solid
• Molecular weight: 692.7000122070312

G 418 disulfate salt

CAS: 108321-42-2

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 692.7093600000002

G-418 Disulphate

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Purity: The product has been tested (Typical Value in Batch COA)
• Color and Shape: solid
• Molecular weight: 692.71g/mol

G-418 disulfate

CAS: 108321-42-2

• Purity: 99.78%
• Molecular weight: 692.71g/mol

G-418 Sulphate solution 50mg/ml

CAS: 108321-42-2

• Color and Shape: Solution
• Molecular weight: 594.63g/mol

G418 disulphate salt

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀· 2H₂SO₄
• Purity: ≥ 720μg/mg
• Color and Shape: White to almost white powder
• Molecular weight: 692.71

G418 disulphate salt, 10% solution in water

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀· 2H₂SO₄
• Color and Shape: Clear, colourless liquid
• Molecular weight: 692.71

G418 Disulfate

CAS: 108321-42-249863-47-0

• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Purity: >90.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 692.70

G418 sulfate, for biochemistry

CAS: 108321-42-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Color and Shape: Powder, White to off-white
• Molecular weight: 692.70

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the …

• Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S
• Purity: 98% - 99.9%
• Color and Shape: White To Off-White Powder
• Molecular weight: 692.71

Geneticin Disulfate

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀· 2H₂O₄S
• Molecular weight: 496.56 2*98.07

G-418.Sulfate, Sterile-Filtered Solution

CAS: 108321-42-2

M01802 - G-418.Sulfate, Sterile-Filtered Solution

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Purity: >90.0%(HPLC)(N)
• Color and Shape: Liquid
• Molecular weight: 692.7000122070312

Geneticin sulfate

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections …

• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 692.71 g/mol

G-418 Sulphate (Geneticin) for tissue culture

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Color and Shape: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow
• Molecular weight: 692.70

G-418 Sulphate (Geneticin) extrapure

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Color and Shape: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow
• Molecular weight: 692.70

Geneticin Disulfate Salt

CAS: 108321-42-2

• Formula: C₂₀H₄₀N₄O₁₀H₂O₄S
• Color and Shape: Neat
• Molecular weight: 692.71

Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections …

• Formula: C₂₀H₄₄N₄O₁₈S₂
• Purity: Min. 97.0 Area-%
• Molecular weight: 692.71 g/mol