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CAS 108549-23-1

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Dibenzyl diisopropylphosphoramidite

Description:
Dibenzyl diisopropylphosphoramidite is a chemical compound characterized by its phosphoramidite functional group, which is commonly used in organic synthesis, particularly in the field of oligonucleotide chemistry. This compound features two benzyl groups and two isopropyl groups attached to a phosphorus atom, contributing to its steric bulk and influencing its reactivity. It is typically a colorless to pale yellow liquid at room temperature and is known for its ability to act as a protecting group for hydroxyl functionalities in nucleosides and nucleotides. The presence of the phosphoramidite moiety allows for the formation of phosphodiester bonds, making it a crucial reagent in the synthesis of DNA and RNA sequences. Additionally, dibenzyl diisopropylphosphoramidite is sensitive to moisture and air, necessitating careful handling and storage under inert conditions. Its applications extend beyond nucleic acid synthesis to include potential uses in various organic transformations and as a building block in the development of phosphorous-containing compounds.
Formula:C20H28NO2P
InChI:InChI=1/C20H28NO2P/c1-17(2)21(18(3)4)24(22-15-19-11-7-5-8-12-19)23-16-20-13-9-6-10-14-20/h5-14,17-18H,15-16H2,1-4H3
InChI key:ANPWLBTUUNFQIO-UHFFFAOYSA-N
SMILES:CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1
Synonyms:
  • Bis(benzyloxy)(diisopropylamino)phosphine
  • Bis-bzl-2iPr-P
  • Phosphoramidous acid, bis(1-methylethyl)-, bis(phenylmethyl) ester
  • Dibenzyl Dipropan-2-Ylphosphoramidoite
  • Dibenzyl N,N-diisopropylphosphoramidite
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